87976-71-4

Basic information

• Product Name: PYRUVIC ACID, SODIUM SALT (1-13C)
• Synonyms: SODIUM PYRUVATE (1-13C);PYRUVIC ACID, SODIUM SALT (1-13C);PYRUVIC-1-13C ACID SODIUM SALT;PYRUVIC-1-13C ACID, SODIUM SALT, 99 ATOM % 13C;pyruvic acid-1-13c sodium salt;SODIUM PYRUVATE(1-13C), 5 - 10% DIMER;Sodium pyruvate-1-13C
• CAS NO: 87976-71-4
• Molecular Formula: C₃H₃O₃*Na
• Molecular Weight: 111.05
• Mol File: 87976-71-4.mol

Chemical Properties

• Melting Point: >300 °C(lit.)
• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: PYRUVIC ACID, SODIUM SALT (1-13C)(CAS DataBase Reference)
• NIST Chemistry Reference: PYRUVIC ACID, SODIUM SALT (1-13C)(87976-71-4)
• EPA Substance Registry System: PYRUVIC ACID, SODIUM SALT (1-13C)(87976-71-4)

Safety Data

• WGK Germany: 3
• Hazardous Substances Data: 87976-71-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C3H4O3.Na/c1-2(4)3(5)6;/h1H3,(H,5,6);/q;+1/p-1/i3+1;

Upstream product

• 99124-30-8 [1-¹³C] pyruvic acid 
• 127-17-3 2-oxo-propionic acid 

Relevant articles and documents

SYSTEMS AND METHOD FOR GENERATION OF HYPERPOLARIZED MATERIALS

A method for preparing an NMR material, comprising generating parahydrogen in gas or liquid form at a first location; transporting the parahydrogen away from the first location; mixing a precursor compound including a metabolite component with a catalyst for hydrogenation; hydrogenating the precursor compound using the parahydrogen; transferring polarization in the precursor compound to a nuclear spin of the metabolite component; cleaving a side arm of the precursor compound in a chemical reaction, with the metabolite molecule being one of the products of the reaction; separating the metabolite molecule from the catalyst for hydrogenation and other products of the reaction; and generating metabolite molecules for use in an MRI scanner by extracting a sample of the metabolite molecule having at least 5% polarization.

Synthesis of isotopically labeled alpha-keto acids and esters

Isotopically labeled alpha-keto acids and esters are disclosed herein. Also disclosed are methods of synthesizing isotopically labeled alpha-keto acids and esters.

METHOD OF PRODUCING A COMPOSITION, COMPOSITION AND ITS USE

The invention relates to a method of producing a composition comprising hyperpolarised 13C-pyruvate, the composition and its use as an imaging agent for MR imaging.

Synthesis of [1-13C]pyruvic acid], [2-13C]pyruvic acid], [3-13C]pyruvic acid] and combinations thereof

The present invention is directed to labeled compounds, of the formulae wherein C* is each independently selected from the group consisting of 13C and 12C with the proviso that at least one C* is 13C, each hydrogen of the

RADICALS AND THEIR USE AS PARAMAGNETIC AGENTS IN A DNP PROCESS

The invention relates to new radicals, their use as paramagnetic agents in a method for the dynamic nuclear polarisation and a method for the dynamic nuclear polarisation of compounds comprising carboxyl groups.

METHOD OF TUMOUR IMAGING

The invention relates to a method tumour imaging using hyperpolarised 13C-pyruvate as MR imaging agent, the method allowing for the discrimination between tumour tissue and healthy tissue.