- Antitumour indolequinones: Synthesis and activity against human pancreatic cancer cells
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An important determinant of the growth inhibitory activity of indolequinones against pancreatic cancer cells is substitution on the 2-position with 2-unsubstituted derivatives being markedly more potent. A series of indolequinones bearing a range of subst
- Inman, Martyn,Visconti, Andrea,Yan, Chao,Siegel, David,Ross, David,Moody, Christopher J.
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p. 4848 - 4861
(2014/07/07)
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- A Short, Convergent Synthesis of Aristolindiquinone
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Aristolindiquinone, 2,5-dihydroxy-3,8-dimethyl-1,4-naphthoquinone 1, is synthesised by the regiochemical addition of 1-methoxy-1-trimethylsiloxypenta-1,3-diene 2 to 5-bromo-2-methoxy-3-methyl-1,4-benzoquinone 3.The regioisomer 2,8-dihydroxy-3,5-dimethyl-1
- Botha, Marc E.,Giles, Robin G. F.,Yorke, Selwyn C.
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- Regiospecific and highly stereoselective formation of benzisochroman-6,9-quinones. Synthesis of (±)-ventilagone and (±)-ventiloquinone H
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An approach known to give regiospecific cycloadditions over a wide range of substrates has been applied to the synthesis of (±)-ventilagone and (±)-ventiloquinone H using a novel, electron-rich heterocyclic diene. The strategy provides for the sole format
- Blouin,Beland,Brassard
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p. 1466 - 1471
(2007/10/02)
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