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88107-10-2

Articles about 88107-10-2Total 3 be found

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Disubstituted tetrazole leukotriene antagonists and methods for their use thereas
The instant invention provides disubstituted tetrazoles that antagonizes the effect of leukotrienes C4, D4 or E4 or any combination thereof in selected tissues. The disubstituted tetrazoles are used in pharmaceutical formulations and methods of treatment of conditions caused by excessive release or production of leukotrienes C4, D4 or E4 or any combination thereof. Such conditions include an immediate hypersensitivity reaction of the type represented by asthma, or by shock or other adverse cardiovascular effects.
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(2008/06/13)

Leukotriene antagonists
This invention provides novel alkane derivatives which are leukotriene antagonists, formulations of those derivatives, and a method of using those derivatives for the treatment of conditions characterized by an excessive release of leukotrienes.
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(2008/06/13)

Improved conditions for the formation of tetrazoles
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Bernstein,Vacek
p. 1133 - 1134
(2007/10/02)

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Chemical Properties

Melting Point: 117-119℃
Boiling Point: 553 °C at 760 mmHg
Flash Point:288.3 °C
Density: 1.22 g/cm³
Solubility:Soluble in DMSO (up to 30 mg/ml) or in Ethanol (up to 15 mg/ml),
Storage Temp.:Store at +4°C
Vapor Pressure: 7.73E-13mmHg at 25°C
Refractive Index: 1.574
PKA: 5.02±0.10(Predicted)
PSA: 100.99000
LogP: 2.46210

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