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6-BROMO-4-FLUORO-2,3-DIHYDRO-1H-INDEN-1-ONE, also known as BFI, is a chemical compound characterized by its molecular formula C9H6BrFO. It presents as a yellow to light brown solid that is insoluble in water. 6-BROMO-4-FLUORO-2,3-DIHYDRO-1H-INDEN-1-ONE is a significant entity in the realms of organic synthesis and pharmaceutical research, primarily utilized for the development of innovative drugs. Its applications extend to the creation of pharmaceuticals and agrochemicals, leveraging its potential antitumor, anti-inflammatory, and antioxidant properties. Furthermore, BFI serves as a crucial precursor in the synthesis of various heterocyclic compounds, underscoring its value in medicinal chemistry.

881189-74-8

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881189-74-8 Usage

Uses

Used in Pharmaceutical Research and Development:
6-BROMO-4-FLUORO-2,3-DIHYDRO-1H-INDEN-1-ONE is used as a key intermediate in the synthesis of new drugs for various therapeutic applications due to its unique chemical structure and properties.
Used in Medicinal Chemistry:
BFI is utilized as a building block for the production of pharmaceuticals and agrochemicals, capitalizing on its potential antitumor, anti-inflammatory, and antioxidant properties to enhance the efficacy of these products.
Used in Organic Synthesis:
6-BROMO-4-FLUORO-2,3-DIHYDRO-1H-INDEN-1-ONE is employed as a precursor in the synthesis of heterocyclic compounds, which are vital in the development of a wide range of chemical products, including pharmaceuticals and agrochemicals.
Used in Antitumor Applications:
In the field of oncology, BFI is used as a compound with potential antitumor properties, contributing to the development of treatments aimed at inhibiting tumor growth and progression.
Used in Anti-inflammatory Applications:
6-BROMO-4-FLUORO-2,3-DIHYDRO-1H-INDEN-1-ONE is applied in anti-inflammatory research and drug development, potentially offering new avenues for managing inflammation-related conditions.
Used in Antioxidant Applications:
BFI is used in antioxidant formulations, leveraging its properties to combat oxidative stress and related diseases, thereby contributing to the development of health and wellness products.

Check Digit Verification of cas no

The CAS Registry Mumber 881189-74-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,1,1,8 and 9 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 881189-74:
(8*8)+(7*8)+(6*1)+(5*1)+(4*8)+(3*9)+(2*7)+(1*4)=208
208 % 10 = 8
So 881189-74-8 is a valid CAS Registry Number.

881189-74-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-bromo-4-fluoroindan-1-one

1.2 Other means of identification

Product number -
Other names 6-BROMO-4-FLUORO-2,3-DIHYDRO-1H-INDEN-1-ONE

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:881189-74-8 SDS

881189-74-8Downstream Products

881189-74-8Relevant articles and documents

Potent Inhibitors of Plasmodial Serine Hydroxymethyltransferase (SHMT) Featuring a Spirocyclic Scaffold

Schwertz, Geoffrey,Witschel, Matthias C.,Rottmann, Matthias,Leartsakulpanich, Ubolsree,Chitnumsub, Penchit,Jaruwat, Aritsara,Amornwatcharapong, Watcharee,Ittarat, Wanwipa,Sch?fer, Anja,Aponte, Raphael A.,Trapp, Nils,Chaiyen, Pimchai,Diederich, Fran?ois

, p. 931 - 943 (2018/04/20)

With the discovery that serine hydroxymethyltransferase (SHMT) is a druggable target for antimalarials, the aim of this study was to design novel inhibitors of this key enzyme in the folate biosynthesis cycle. Herein, 19 novel spirocyclic ligands based on

CYCLIC AMINE DERIVATIVE OR SALT THEREOF

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Page/Page column 23; 44, (2010/11/27)

Provided are compounds which are an NMDA antagonist having a broad safety margin and are useful as a treating agent or a preventing agent for Alzheimer's disease, cerebrovascular dementia, Parkinson's disease, ischemic apoplexy, pain, etc. Concretely prov

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