- First chemical synthesis of three natural depsides involved in flavonol catabolism and related to quercetinase catalysis
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We report here the first chemical synthesis of three depsides related to quercetinase-catalyzed degradation of kaempferol, quercetin, and myricetin. The three depsides were constructed through the coupling of suitably protected phloroglucinol carboxylic acid and hydroxy-perbenzylated, derivatives of gallic, protocatechuic, and 4-hydroxy benzoic acids. The three synthesized target compounds proved to be identical to their natural counterparts, arising from quercetinase action on corresponding flavonols. Copyright Taylor & Francis Group, LLC.
- Tranchimand, Sylvain,Tron, Thierry,Gaudin, Christian,Iacazio, Gilles
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p. 587 - 597
(2007/10/03)
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