884494-54-6

Basic information

• Product Name: 2-CHLORO-5-FLUORO-4-FORMYLPYRIDINE
• Synonyms: 2-CHLORO-5-FLUORO-4-FORMYLPYRIDINE;2-CHLORO-4-FORMYL-5-FLUOROPYRIDINE;2-CHLORO-5-FLUOROISONICOTINALDEHYDE;4-Pyridinecarboxaldehyde, 2-chloro-5-fluoro-;2-Chloro-5-fluoropyridine-4-carboxaldehyde;2-chloro-5-fluoro-3-forMylpyridine-4-carboxylic acid
• CAS NO: 884494-54-6
• Molecular Formula: C₆H₃ClFNO
• Molecular Weight: 159.55
• Product Categories: API intermediates;Boronic Acid
• Mol File: 884494-54-6.mol

Chemical Properties

• Boiling Point: 228℃
• Flash Point: 91℃
• Appearance: /
• Density: 1.444
• Vapor Pressure: 0.077mmHg at 25°C
• Refractive Index: 1.565
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 2-CHLORO-5-FLUORO-4-FORMYLPYRIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-CHLORO-5-FLUORO-4-FORMYLPYRIDINE(884494-54-6)
• EPA Substance Registry System: 2-CHLORO-5-FLUORO-4-FORMYLPYRIDINE(884494-54-6)

Safety Data

• Hazardous Substances Data: 884494-54-6(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Chloro-5-fluoro-4-formylpyridine is used as a key intermediate in the synthesis of various pharmaceuticals. Its unique structure and functional groups make it a valuable component in the development of new drugs with specific therapeutic properties.
Used in Agrochemical Industry:
In the agrochemical industry, 2-Chloro-5-fluoro-4-formylpyridine is utilized as an intermediate for the production of agrochemicals. Its incorporation into these compounds can enhance their effectiveness in pest control and crop protection.
Used in Organic Chemistry:
As a building block in organic chemistry, 2-Chloro-5-fluoro-4-formylpyridine is employed in the synthesis of various organic compounds. Its versatility and reactivity contribute to the creation of a wide range of chemical products.
Safety Precautions:
It is important to handle 2-Chloro-5-fluoro-4-formylpyridine with care, as it is considered harmful if swallowed or inhaled and may cause irritation to the skin and eyes. Proper safety measures, such as wearing protective clothing and using appropriate ventilation, should be taken during its use and storage.

InChI:InChI=1/C6H3ClFNO/c7-6-1-4(3-10)5(8)2-9-6/h1-3H

Upstream product

• 31301-51-6 2-chloro-5-fluoropyridine 
• 68-12-2 N,N-dimethyl-formamide 

Downstream Products

• 1005343-07-6 (5-fluoro-(S)-4-{1-[(R)-1-(4-methoxyphenyl)ethyl]pyrrolidin-2-yl}pyridin-2-yl)-(4-fluorophenyl)methylamine 
• 1005343-06-5 2-chloro-5-fluoro-(S)-4-{-1-[(R)-1-(4-methoxyphenyl)ethyl]pyrrolidin-2-yl}pyridine 

Relevant articles and documents

Heterocyclic compound as FGFR inhibitor, synthesis method and applications thereof

The present invention discloses a heterocyclic compound as an FGFR inhibitor, and a synthesis method thereof, and applications of the heterocyclic compound in preparation of drugs for treating cancers. According to the present invention, the heterocyclic compound as the FGFR inhibitor or the pharmaceutically acceptable salt thereof has high FGFR inhibitory action, and the pharmaceutical composition prepared from the heterocyclic compound has good anticancer effect and wide application range.

[...] compound and pest control agent

[Problem] pesticidal activity, particularly insecticidal activity and/or acaricidal activity therein, safety, and industrially advantageous [...] compound can be synthesized. 5 - (Ethyl sulfonyl) [a] (1 - methyl - 1H - imidazole (4 - (trifluoromethoxy) ph