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(3-AMINO-4-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER is a chemical compound characterized by the presence of an amino group, a chloro group, and a carbamate functional group. It is a white solid with a molecular formula of C11H14ClN2O2 and a molar mass of 242.69 g/mol. Known by its CAS number 97163-41-6, this compound is utilized as a reagent in organic synthesis and pharmaceutical research. The tert-butyl ester group enhances its stability and ease of handling in laboratory settings. However, due to its potential for skin and eye irritation, it is crucial to handle this chemical with care and adhere to proper safety protocols.

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  • 885270-73-5 Structure
  • Basic information

    1. Product Name: (3-AMINO-4-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER
    2. Synonyms: (3-AMINO-4-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER;tert-Butyl (3-aMino-4-chlorophenyl)carbaMate
    3. CAS NO:885270-73-5
    4. Molecular Formula: C11H15ClN2O2
    5. Molecular Weight: 242.7
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 885270-73-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C(protect from light)
    8. Solubility: N/A
    9. CAS DataBase Reference: (3-AMINO-4-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
    10. NIST Chemistry Reference: (3-AMINO-4-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER(885270-73-5)
    11. EPA Substance Registry System: (3-AMINO-4-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER(885270-73-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: 43
    3. Safety Statements: 36/37
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 885270-73-5(Hazardous Substances Data)

885270-73-5 Usage

Uses

Used in Organic Synthesis:
(3-AMINO-4-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER is used as a reagent in organic synthesis for its ability to participate in various chemical reactions, facilitating the formation of new compounds with desired properties.
Used in Pharmaceutical Research:
In the pharmaceutical industry, (3-AMINO-4-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER is used as a research compound to explore its potential applications in drug development. Its unique structure allows scientists to investigate its interactions with biological targets and evaluate its efficacy in treating specific conditions.
Used in Laboratory Settings:
Due to its stability and ease of handling, (3-AMINO-4-CHLORO-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER is used in laboratory settings for educational purposes and as a component in various experimental procedures. Its properties make it suitable for teaching and learning about chemical reactions and synthesis processes.

Check Digit Verification of cas no

The CAS Registry Mumber 885270-73-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,2,7 and 0 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 885270-73:
(8*8)+(7*8)+(6*5)+(5*2)+(4*7)+(3*0)+(2*7)+(1*3)=205
205 % 10 = 5
So 885270-73-5 is a valid CAS Registry Number.

885270-73-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name tert-butyl N-(3-amino-4-chlorophenyl)carbamate

1.2 Other means of identification

Product number -
Other names 2-Amino-4-Boc-amino-phenylchloride

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:885270-73-5 SDS

885270-73-5Relevant articles and documents

Design, Synthesis, and Characterization of a Fluorescence Polarization Pan-BET Bromodomain Probe

Paulson, Carolyn N.,Guan, Xianghong,Ayoub, Alex M.,Chan, Alice,Karim, Rezaul M.,Pomerantz, William C.K.,Sch?nbrunn, Ernst,Georg, Gunda I.,Hawkinson, Jon E.

, p. 1223 - 1229 (2018)

Several chemical probes have been developed for use in fluorescence polarization screening assays to aid in drug discovery for the bromodomain and extra-terminal domain (BET) proteins. However, few of those have been characterized in the literature. We ha

Differential BET Bromodomain Inhibition by Dihydropteridinone and Pyrimidodiazepinone Kinase Inhibitors

Karim, Rezaul Md,Bikowitz, Melissa J.,Chan, Alice,Zhu, Jin-Yi,Grassie, Dylan,Becker, Andreas,Berndt, Norbert,Gunawan, Steven,Lawrence, Nicholas J.,Sch?nbrunn, Ernst

, p. 15772 - 15786 (2021/11/16)

BRD4 and other members of the bromodomain and extraterminal (BET) family of proteins are promising epigenetic targets for the development of novel therapeutics. Among the reported BRD4 inhibitors are dihydropteridinones and benzopyrimidodiazepinones origi

BRD4-KINASE INHIBITORS AS CANCER THERAPEUTICS

-

Page/Page column 241-242, (2017/05/02)

Disclosed herein are compounds that are inhibitors of BDR4 and their use in the treatment of cancer. Methods of screening for selective inhibitors of BDR4 are also disclosed. In certain aspects, disclosed are compounds of Formula I through IV.

POTENT DUAL BRD4-KINASE INHIBITORS AS CANCER THERAPEUTICS

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Page/Page column 130, (2016/04/26)

Disclosed herein are compounds that are inhibitors of BRD4 and their use in the treatment of cancer. Methods of screening for selective inhibitors of BRD4 are also disclosed. In certain aspects, disclosed are compounds of Formula I-IV.

PYRAZOLE PYRAZINE AMINE COMPOUNDS AS KINASE INHIBITORS, COMPOSITIONS THEREOF AND METHODS OF TREATMENT THEREWITH

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Page/Page column 123, (2009/09/04)

Provided herein are Pyrazole Pyrazine Amine Compounds having the following structure:Formula (I). Wherein Q and R1-R3 are as defined herein, compositions comprising an effective amount of a Pyrazole Pyrazine Amine Compound and methods for treating or preventing inflammatory conditions, immunological conditions, cancer, neurodegenerative diseases, age-related diseases, cardiovascular diseases and metabolic conditions, or conditions treatable or preventable by inhibition of an IKK, or an IKK pathway, comprising administering an effective amount of a Pyrazole Pyrazine Amine Compound to a patient in need thereof.

NOVEL CHEMICAL COMPOUNDS

-

, (2008/06/13)

This invention relates to newly identified compounds for inhibiting hYAK3 proteins and methods for treating diseases associated with hYAK3 activity.

NOVEL CHEMICAL COMPOUNDS

-

Page/Page column 74, (2010/11/25)

This invention relates to newly identified compounds for inhibiting hYAK3 proteins and methods for treating diseases associated with hYAK3 activity.

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