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6-Bromo-imidazo[1,2-a]pyridine-2-carboxaldehyde is a heterocyclic aromatic compound with the molecular formula C8H5BrN2O. It features a pyridine ring fused with an imidazole ring and a bromine atom at the 6-position. This chemical is known for its versatility as a building block in the synthesis of pharmaceuticals and agrochemicals, as well as its potential applications in organic synthesis, medicinal chemistry, and material science. The aldehyde functional group in its structure contributes to its reactivity and ability to form diverse compounds with potential biological and industrial significance.

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  • 885276-09-5 Structure
  • Basic information

    1. Product Name: 6-BROMO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXALDEHYDE
    2. Synonyms: 6-BROMO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXALDEHYDE;Imidazo[1,2-a]pyridine-2-carboxaldehyde, 6-bromo-
    3. CAS NO:885276-09-5
    4. Molecular Formula: C8H5BrN2O
    5. Molecular Weight: 225.05
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 885276-09-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.73±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
    8. Solubility: N/A
    9. PKA: 1.65±0.50(Predicted)
    10. CAS DataBase Reference: 6-BROMO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXALDEHYDE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 6-BROMO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXALDEHYDE(885276-09-5)
    12. EPA Substance Registry System: 6-BROMO-IMIDAZO[1,2-A]PYRIDINE-2-CARBOXALDEHYDE(885276-09-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 885276-09-5(Hazardous Substances Data)

885276-09-5 Usage

Uses

Used in Pharmaceutical Synthesis:
6-Bromo-imidazo[1,2-a]pyridine-2-carboxaldehyde is used as a key intermediate in the synthesis of various pharmaceutical compounds. Its unique structure and reactivity allow for the creation of diverse molecules with potential therapeutic applications.
Used in Agrochemical Synthesis:
In the agrochemical industry, 6-Bromo-imidazo[1,2-a]pyridine-2-carboxaldehyde serves as a building block for the development of new agrochemicals, such as pesticides and herbicides, due to its ability to form a wide range of chemical structures.
Used in Organic Synthesis:
6-Bromo-imidazo[1,2-a]pyridine-2-carboxaldehyde is utilized as a versatile intermediate in organic synthesis, enabling the formation of various complex organic compounds with potential applications in different fields.
Used in Medicinal Chemistry:
In medicinal chemistry, 6-Bromo-imidazo[1,2-a]pyridine-2-carboxaldehyde is employed as a starting material for the development of new drugs and drug candidates, thanks to its unique structure and reactivity.
Used in Material Science:
6-Bromo-imidazo[1,2-a]pyridine-2-carboxaldehyde has potential applications in material science, where its unique structure and properties can be exploited to develop new materials with specific characteristics and functions.

Check Digit Verification of cas no

The CAS Registry Mumber 885276-09-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,2,7 and 6 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 885276-09:
(8*8)+(7*8)+(6*5)+(5*2)+(4*7)+(3*6)+(2*0)+(1*9)=215
215 % 10 = 5
So 885276-09-5 is a valid CAS Registry Number.

885276-09-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 6-bromoimidazo[1,2-a]pyridine-2-carbaldehyde

1.2 Other means of identification

Product number -
Other names QC-8071

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:885276-09-5 SDS

885276-09-5Downstream Products

885276-09-5Relevant articles and documents

HETEROCYCLIC COMPOUNDS AS MUTANT IDH INHIBITORS

-

Paragraph 0360; 0362, (2020/07/16)

The present disclosure relates generally to compounds useful in treatment of conditions associated with mutant isocitrate dehydrogenase (mt-IDH), particularly mutant IDH1 enzymes. Specifically, the present invention discloses compound of formula (IA), which exhibits inhibitory activity against mutant IDH1 enzymes. Method of treating conditions associated with excessive activity of mutant IDH1 enzymes with such compound is disclosed. Uses thereof, pharmaceutical composition, and kits are also disclosed.

Diversity-Oriented Synthesis of β-Lactams and γ-Lactams by Post-Ugi Nucleophilic Cyclization: Lewis Acids as Regioselective Switch

Li, Zhenghua,Sharma, Upendra Kumar,Liu, Zhen,Sharma, Nandini,Harvey, Jeremy N.,Van Der Eycken, Erik V.

supporting information, p. 3957 - 3962 (2015/06/30)

Heterocyclic fused α-methylene β-lactams were successfully synthesized by a post-Ugi InIII-catalyzed intramolecular addition reaction. Switching from InCl3 to AlCl3 led to the regioselective synthesis of α,β-unsaturated γ-lactams. Moreover, replacing terminal alkynes by substituted alkynes in the Ugi adducts resulted in the exclusive formation of γ-lactams with both catalytic systems. A regioselective approach for the synthesis of heterocyclic fused α-methylene β-lactams and α,β-unsaturated γ-lactams by employing a Ugi reaction followed by InIII- or AlIII-catalyzed intramolecular nucleophilic addition is reported.

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