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Methyl 4-bromo-6-(1H)-indazole-1-carboxylate is a chemical compound that belongs to the indazole class. It is characterized by the presence of a methyl group, a bromine atom, and a carboxylate group attached to a 6-membered ring of the indazole molecule. This unique structure and reactivity make it a promising candidate for various applications in organic synthesis and pharmaceutical research.

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  • 885518-47-8 Structure
  • Basic information

    1. Product Name: Methyl 4-bromo-6-(1H)-ind...
    2. Synonyms: Methyl 4-bromo-6-(1H)-ind...;Methyl 4-broMo-1H-indazole-6-carboxylate;Methyl 4-broMo-6-(1H)-indazole carboxylate;1H-Indazole-6-carboxylicacid,4-broMo-,Methylester;4-BroMo-1H-indazole-6-carboxylic acid Methyl ester
    3. CAS NO:885518-47-8
    4. Molecular Formula: C9H7BrN2O2
    5. Molecular Weight: 255.06808
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 885518-47-8.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 395.9±22.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.709
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. PKA: 11.21±0.40(Predicted)
    10. CAS DataBase Reference: Methyl 4-bromo-6-(1H)-ind...(CAS DataBase Reference)
    11. NIST Chemistry Reference: Methyl 4-bromo-6-(1H)-ind...(885518-47-8)
    12. EPA Substance Registry System: Methyl 4-bromo-6-(1H)-ind...(885518-47-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 885518-47-8(Hazardous Substances Data)

885518-47-8 Usage

Uses

Used in Organic Synthesis:
Methyl 4-bromo-6-(1H)-indazole-1-carboxylate is used as an intermediate in the synthesis of various organic compounds. Its unique structure and reactivity allow for the formation of new chemical bonds and the creation of diverse molecular structures.
Used in Pharmaceutical Research:
Methyl 4-bromo-6-(1H)-indazole-1-carboxylate is used as a starting material or intermediate in the development of new pharmaceuticals. Its properties and reactivity make it a valuable component in the synthesis of potential drug candidates.
Used in Drug Production:
Methyl 4-bromo-6-(1H)-indazole-1-carboxylate is used as an important intermediate in the production of various drugs. Its unique structure and reactivity contribute to the development of new therapeutic agents with improved efficacy and safety profiles.
Used in Biological and Pharmacological Studies:
Methyl 4-bromo-6-(1H)-indazole-1-carboxylate may exhibit biological activities and pharmacological effects that make it valuable for further study. Its potential applications in this area could lead to the discovery of new therapeutic agents and a better understanding of its mechanisms of action.

Check Digit Verification of cas no

The CAS Registry Mumber 885518-47-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 8,8,5,5,1 and 8 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 885518-47:
(8*8)+(7*8)+(6*5)+(5*5)+(4*1)+(3*8)+(2*4)+(1*7)=218
218 % 10 = 8
So 885518-47-8 is a valid CAS Registry Number.

885518-47-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 14, 2017

Revision Date: Aug 14, 2017

1.Identification

1.1 GHS Product identifier

Product name Methyl 4-bromo-1H-indazole-6-carboxylate

1.2 Other means of identification

Product number -
Other names methyl 4-bromo-1H-indazole-6-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:885518-47-8 SDS

885518-47-8Relevant articles and documents

SELECTIVE INHIBITORS OF CLINICALLY IMPORTANT MUTANTS OF THE EGFR TYROSINE KINASE

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, (2019/01/21)

The present invention provides compounds of Formula (I) or a subgeneric structure or species thereof, or a pharmaceutically acceptable salt, ester, solvate, and/or prodrug thereof, and methods and compositions for treating or ameliorating abnormal cell pr

CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF

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, (2017/03/21)

Carboxy-substituted (hetero)aryl derivatives, pharmaceutical compositions comprising these compounds, and methods of preparing such compounds and compositions are provided. The compounds or compositions are useful in inhibiting xanthine oxidase and urate anion transporter 1, and also can be used in the treatment or prevention of diseases associated with high blood uric acid level in mammals, especially humans.

Synthesis of substituted 4-(1H-indol-6-yl)-1H-indazoles as potential PDK1 inhibitors

Brzozowski, Martin,O'Brien, Nathan J.,Wilson, David J.D.,Abbott, Belinda M.

, p. 318 - 326 (2014/01/06)

The development of a preparative route to a series of novel 4-(1H-indol-6-yl)-1H-indazole compounds as potential PDK1 inhibitors is described. The synthetic strategy centres on the late-stage Suzuki cross-coupling of N-unprotected indazole and indole frag

COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS

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Page/Page column 36, (2011/04/25)

The invention provides a novel class of compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with abnormal or deregulated kinase activity, particularly di

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