885519-98-2

Basic information

• Product Name: 1H-Indazole-5-carboxylicacid,3-forMyl-
• Synonyms: 1H-Indazole-5-carboxylicacid,3-forMyl-;3-ForMyl-1H-indazole-5-carboxylic;3-Formyl-5-indazole carbocylic acid
• CAS NO: 885519-98-2
• Molecular Formula: C9H6N2O3
• Molecular Weight: 190.15554
• Mol File: 885519-98-2.mol

Chemical Properties

• Boiling Point: 521.9±30.0 °C(Predicted)
• Appearance: /
• Density: 1.594±0.06 g/cm3(Predicted)
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• PKA: 3.76±0.30(Predicted)
• CAS DataBase Reference: 1H-Indazole-5-carboxylicacid,3-forMyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indazole-5-carboxylicacid,3-forMyl-(885519-98-2)
• EPA Substance Registry System: 1H-Indazole-5-carboxylicacid,3-forMyl-(885519-98-2)

Safety Data

• Hazardous Substances Data: 885519-98-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
1H-Indazole-5-carboxylic acid, 3-formylis used as a kinase inhibitor for the development of therapeutic agents. Kinase inhibitors are a class of drugs that target specific enzymes involved in cellular signaling pathways, playing a crucial role in the regulation of various cellular processes, including cell growth, differentiation, and apoptosis. By inhibiting the activity of these enzymes, 1H-Indazole-5-carboxylic acid, 3-formylcan potentially be used in the treatment of various diseases, such as cancer and inflammatory disorders.
Used in Chemical Synthesis:
1H-Indazole-5-carboxylic acid, 3-formylcan also be used as a building block or intermediate in the synthesis of more complex organic compounds. Its unique structure and functional groups make it a valuable component in the development of new pharmaceuticals, agrochemicals, and other specialty chemicals.

InChI:InChI=1S/C9H6N2O3/c12-4-8-6-3-5(9(13)14)1-2-7(6)10-11-8/h1-4H,(H,10,11)(H,13,14)

Upstream product

• 1670-81-1 1H-Indole-5-carboxylic acid 

Relevant articles and documents

An optimized procedure for direct access to 1: H -indazole-3-carboxaldehyde derivatives by nitrosation of indoles

Indazole derivatives are currently drawing more and more attention in medicinal chemistry as kinase inhibitors. 1H-indazole-3-carboxaldehydes are key intermediates to access to a variety of polyfunctionalized 3-substituted indazoles. We report here a general access to this motif, based on the nitrosation of indoles in a slightly acidic environment. These very mild conditions allow the conversion of both electron-rich and electron-deficient indoles into 1H-indazole-3-carboxaldehydes.

SUBSTITUTED INDAZOLE DERIVATIVES, THEIR MANUFACTURE AND USE AS PHARMACEUTICAL AGENTS

Objects of the present invention are the compounds of formula (I) their pharmaceutically acceptable salts, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, medicaments containing them and their manufact

Tricyclic heterocycles

The present invention relates to the compounds of formula I their pharmaceutically acceptable salts or esters, enantiomeric forms, diastereoisomers and racemates, the preparation of the above-mentioned compounds, pharmaceutical compositions containing suc