cas 885522-63-4, 3-IODO-4-METHYL (1H)INDAZOLE

The present invention relates to compounds of formula (I), to the process for preparing such compounds and to their use in the treatment of a pathological condition or disease susceptible to amelioration by CRTh2 antagonist activity.

A straightforward and effective procedure for the preparation of 1H-indazole-3-carboxylic acid esters and amides was developed. A series of functionalized 3-iodoindazoles were subjected to Pd-catalyzed carbonylations in the presence of methanol or amines,

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Chemical Properties

Boiling Point: 368.6oC at 760 mmHg

Flash Point:176.7oC

Density: 1.933g/cm3

Storage Temp.:Room temperature.

Vapor Pressure: 2.66E-05mmHg at 25°C

PSA: 28.68000

LogP: 2.47590

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