885524-15-2

Basic information

• Product Name: 4-CHLORO-1-(3,5-DIMETHYLPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDINE
• Synonyms: 4-CHLORO-1-(3,5-DIMETHYLPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDINE
• CAS NO: 885524-15-2
• Molecular Formula: C₁₃H₁₁ClN₄
• Molecular Weight: 258.71
• Mol File: 885524-15-2.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-CHLORO-1-(3,5-DIMETHYLPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-CHLORO-1-(3,5-DIMETHYLPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDINE(885524-15-2)
• EPA Substance Registry System: 4-CHLORO-1-(3,5-DIMETHYLPHENYL)-1H-PYRAZOLO[3,4-D]PYRIMIDINE(885524-15-2)

Safety Data

• Hazardous Substances Data: 885524-15-2(Hazardous Substances Data)

Upstream product

• 852840-43-8 1-(3,5-Dimethyl-phenyl)-1,5-dihydro-pyrazolo[3,4-d]pyrimidine-4-one 
• 852840-43-8 1-(3,5-dimethylphenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-ol 

Downstream Products

• 955320-15-7 1-(3,5-dimethylphenyl)-4-(3-methylpiperidin-1-yl)-1H-pyrazolo[3,4-d]pyrimidine 
• 1175086-31-3 benzo[1,3]dioxol-5-ylmethyl-[1-(3,5-dimethyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-yl]amine 
• 1175086-32-4 [1-(3,5-Dimethyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidine-4-yl]-[2-(2-methoxy-ethoxy)-ethyl]-amine 
• 1175086-30-2 (2,3-dihydro-benzo[1,4]dioxin-6-ylmethyl)-[1-(3,5-dimethyl-phenyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl]-amine 

Relevant articles and documents

NOVEL PYRAZOLO [3, 4 -D] PYRIMIDINE DERIVATIVES AS ANTI-CANCER AGENTS

The invention relates to substituted pyrazolo[3,4-d]pyrimidine derivatives of the Formula-(I), or pharmaceutically acceptable salts thereof, which possess anti-proliferative activity such as anti-cancer activity and are accordingly useful in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of substituted pyrazolo[3,4-d]pyrimidine derivatives, to pharmaceutical compositions containing the compound and to its use in the manufacture of medicaments for the production of an anti-proliferative effect in a warm-blooded animal such as man

Microwave-assisted protocols for the expedited synthesis of pyrazolo[1,5-a] and [3,4-d]pyrimidines

General, high-yielding MAOS protocols for the expedited synthesis of functionalized pyrazolo[1,5-a]pyrimidines and pyrazolo[3,4-b]pyrimidines, as well as their pyrazole precursors, are described amenable to an iterative analogue library synthesis strategy for lead optimization.