885957-46-0

Basic information

• Product Name: 2-(3,4-DIETHOXY-PHENYL)-N-HYDROXY-ACETAMIDINE
• Synonyms: 2-(3,4-DIETHOXY-PHENYL)-N-HYDROXY-ACETAMIDINE;BENZENEETHANIMIDAMIDE,3,4-DIETHOXY-N-HYDROXY;(Z)-2-(3,4-diethoxyphenyl)-N-hydroxyethanimidamide
• CAS NO: 885957-46-0
• Molecular Formula: C₁₂H₁₈N₂O₃
• Molecular Weight: 238.28
• Mol File: 885957-46-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 2-(3,4-DIETHOXY-PHENYL)-N-HYDROXY-ACETAMIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-DIETHOXY-PHENYL)-N-HYDROXY-ACETAMIDINE(885957-46-0)
• EPA Substance Registry System: 2-(3,4-DIETHOXY-PHENYL)-N-HYDROXY-ACETAMIDINE(885957-46-0)

Safety Data

• Hazardous Substances Data: 885957-46-0(Hazardous Substances Data)

Usage

Derivative of acetamidine

The compound is derived from acetamidine, which is a chemical structure that serves as the base for this particular compound.

Diethoxyphenyl group

The presence of a diethoxyphenyl group in the compound, which is a phenyl ring substituted with two ethoxy groups (-O-CH2-CH3), contributes to its chemical properties and potential therapeutic effects.

Potential anti-inflammatory properties

2-(3,4-diethoxy-phenyl)-N-hydroxy-acetamidine has been studied for its potential to reduce inflammation, which could be beneficial in treating various inflammatory conditions.

Potential antimalarial properties

The compound has shown promise as an antimalarial agent, which could be useful in combating malaria, a life-threatening disease caused by parasites transmitted through the bite of infected mosquitoes.

Inhibitory activity against heme polymerase

The compound exhibits strong inhibitory activity against the enzyme heme polymerase, which is essential for the survival and reproduction of malaria parasites. By inhibiting this enzyme, the compound could potentially prevent the growth and spread of the parasites, making it a potential therapeutic agent for malaria treatment.

Need for further research

Despite the promising findings, more research is needed to fully determine the effectiveness and safety of 2-(3,4-diethoxy-phenyl)-N-hydroxy-acetamidine for medical use. This includes understanding its pharmacokinetics, potential side effects, and optimal dosing regimens.

Upstream product

• 27472-21-5 3,4-diethoxyphenylacetonitrile 

Relevant articles and documents

MODULATORS OF LIPID STORAGE

Disclosed are compounds of formulas I, II, and III: Formulas I, II, and III wherein R1-R19 and n are as described herein, or pharmaceutically acceptable salts thereof, or an enantiomer thereof or a conjugate thereof wherein the conju