885965-14-0

Basic information

• Product Name: 4-(2-Methoxyphenyl)benzyl alcohol
• Synonyms: 4-(2-Methoxyphenyl)benzyl alcohol;[4-(2-methoxyphenyl)phenyl]methanol
• CAS NO: 885965-14-0
• Molecular Formula: C₁₄H₁₄O₂
• Molecular Weight: 0
• Mol File: 885965-14-0.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-(2-Methoxyphenyl)benzyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(2-Methoxyphenyl)benzyl alcohol(885965-14-0)
• EPA Substance Registry System: 4-(2-Methoxyphenyl)benzyl alcohol(885965-14-0)

Safety Data

• Hazardous Substances Data: 885965-14-0(Hazardous Substances Data)

Upstream product

• 873-75-6 4-bromobenzenemethanol 
• 5720-06-9 2-Methoxyphenylboronic acid 
• 873-76-7 para-Chlorobenzyl alcohol 

Relevant articles and documents

Biaryl pyridine palladacycles nitrogen heterocyclic carbene compound and its preparation and use

The invention discloses an aryl-pyridine cyclic Pd-N heterocyclic carbene compound. The general formula of the compound is described in the specification, wherein X is selected from Cl, Br and I, L is an N-heterocyclic carbene ligand, and Aryl is an aryl. The invention also discloses a preparation method of the compound. The preparation method comprises the following steps of: adding 2-(4-halogen atom phenyl)-pyridine, imidazolium salt, arylboronic acid, halogenated palladium and alkaline into an organic solvent, heating under the protection of gas, filtering after reaction is finished, drying by distillation, and purifying, thus the aryl-pyridine cyclic Pd-N heterocyclic carbene compound is obtained. The compound can serve as a catalyst and is used for catalyzing reaction between halogenated benzyl alcohol and arylboronic acid to synthesize aryl methyl alcohol. The preparation method has the characteristics of various substrates, mild reaction conditions, high yield, economy and high efficiency and has an important practical value.

Water-soluble palladacycles containing hydroxymethyl groups: Synthesis, crystal structures and use as catalysts for amination and Suzuki coupling of reactions

Two water-soluble monophosphine [PPh3 and 2-dicyclohexylphosphino-2′,6′-dimethoxybiphenyl(Sphos)]-palladacycles containing hydroxymethyl groups 2-3 were prepared by cyclopalladation and chloride bridge-splitting reactions. The complexes were characterized by elemental analysis, ESI-MS and NMR. In addition, single-crystal X-ray analysis reveals that they have one-dimensional lamellar structures involving intermolecular hydrogen bonds and π-π interactions. The use of these palladacycles as catalysts for amination and Suzuki coupling of aryl chlorides in water was investigated. Complex 3 was found to be very efficient for these coupling reactions. Additionally, it was also successfully used in Suzuki coupling of (hydroxymethyl)phenylboronic acid for the synthesis of substituted 2-N-heterocyclic biarylmethanols.