An efficient method for synthesis of thiohydantoins with α-amino esters under microwave irradiation
An efficient and simple way for synthesis of thiohydantoins is reported. In the absence of any additional catalysts, a series of thiohydantoins were synthesized with amino esters and isothiocyanates in aqueous medium under microwave irradiation. Excellent isolated yields (up to 98 %) were obtained under mild conditions.
Zhao, Yanmei,Wang, Zhouyu,Jiang, Zhenju,Feng, Hualin,Liu, Li,Wang, Ju