- COUMARIN DERIVATIVES AND METHODS OF USE IN TREATING CYSTIC FIBROSIS, CHRONIC OBSTRUCTIVE PULMONARY DISEASE, AND MISFOLDED PROTEIN DISORDERS
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Novel CFTR corrector compounds that are effective in rescuing halide efflux, delF508-CFTR protein processing, and apical functional chloride ion transport in a cell are provided. Also provided are methods for treating protein folding disorders (e.g., cyst
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Page/Page column 54; 55
(2014/10/04)
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- COUMARIN DERIVATIVES AND METHODS OF USE IN TREATING HYPERPROLIFERATIVE DISEASES
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Coumarin derivative compounds and methods for the treatment of hyperproliferative diseases, such as cancer, polycystic kidney disease, and fibrosis of different tissues (e.g., idiopathic pulmonary fibrosis), are provided. The methods include administering
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Page/Page column 53; 54
(2014/10/04)
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- Synthesis and Analysis of Pheomelanin Degradation Products. 2
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The synthesis of two of the HI degradation products, namely, α-amino-β-(4-hydroxy-7-benzothiazolyl)propionic acid (4) and α-amino-β-(3-hydroxy-4-aminophenyl)propionic acid (5), of the red-brown polymeric pheomelanin pigment are reported.These two amino ac
- Patil, Dilip G.,Chedekel, Miles R.
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p. 997 - 1000
(2007/10/02)
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