887196-25-0

Basic information

• Product Name: 3S,5R isoMer, or (3S,5R)-7-[3-(phenylcarbaMoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calciuM salt
• Synonyms: 3S,5R isoMer, or (3S,5R)-7-[3-(phenylcarbaMoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calciuM salt;Atorvastatin Related CoMpound B;Atorvastatin Related Compound B (20 mg) (3S,5R isomer, or (3S,5R)-7-[3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calcium salt);3-epi-Atorvastatin;calciuM (3S,5R)-7-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbaMoyl)-1H-pyrrol-1-yl)-3,5-dihydroxyheptanoate;Atorvastatin IMpurity-A(EP);Atorvastatin IMpurity-B(EP);Atorvastatin EP IMpurity B
• CAS NO: 887196-25-0
• Molecular Formula: C33H34CaFN2O5+
• Molecular Weight: 597.7098632
• Mol File: 887196-25-0.mol

Chemical Properties

• Melting Point: 160℃ (decomposition)
• Appearance: /
• Storage Temp.: Refrigerator, Under Inert Atmosphere
• Solubility: Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Slightly)
• CAS DataBase Reference: 3S,5R isoMer, or (3S,5R)-7-[3-(phenylcarbaMoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calciuM salt(CAS DataBase Reference)
• NIST Chemistry Reference: 3S,5R isoMer, or (3S,5R)-7-[3-(phenylcarbaMoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calciuM salt(887196-25-0)
• EPA Substance Registry System: 3S,5R isoMer, or (3S,5R)-7-[3-(phenylcarbaMoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calciuM salt(887196-25-0)

Safety Data

• Hazardous Substances Data: 887196-25-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
3S,5R isomer, or (3S,5R)-7-[3-(phenylcarbamoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calcium salt, is used as an isomeric impurity in the development and manufacturing of Atorvastatin Calcium Salt. 3S,5R isoMer, or (3S,5R)-7-[3-(phenylcarbaMoyl)-5-(4-fluorophenyl)-2-isopropyl-4-phenyl-1H-pyrrol-1-yl]-3,5-dihydroxyheptanoic acid calciuM salt is essential for ensuring the purity and quality of Atorvastatin, a drug specifically indicated for lowering elevated LDL-cholesterol and triglycerides in patients with hypercholesterolemia.
As an isomeric impurity, the 3S,5R isomer plays a crucial role in the quality control and regulatory compliance of Atorvastatin Calcium Salt. It helps in monitoring the manufacturing process, ensuring the drug's safety, efficacy, and consistency. Additionally, understanding the properties and behavior of this isomeric impurity can contribute to the optimization of the synthesis process and the development of new pharmaceutical products.