Chlamydocin analogs bearing carbonyl group as possible ligand toward zinc atom in histone deacetylases
A series of chlamydocin analogs with various carbonyl functionalities were designed and synthesized as histone deacetylase (HDAC) inhibitors. Chlamydocin is a cyclic tetrapeptide containing an epoxyketone surrogate in the side chain which makes it irrever
Bhuiyan, Mohammed P.I.,Kato, Tamaki,Okauchi, Tatsuo,Nishino, Norikazu,Maeda, Satoko,Nishino, Tomonori G.,Yoshida, Minoru
p. 3438 - 3446
(2007/10/03)
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