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FMOC-ARG(MTS)-OH is a chemical compound that serves as a derivative of the amino acid arginine, featuring an FMOC (9-fluorenylmethoxycarbonyl) protecting group and a MTS (methanethiosulfonate) modification. FMOC-ARG(MTS)-OH is integral to the processes of peptide synthesis and modification, where the FMOC group temporarily shields the reactive sites of amino acids during solid-phase peptide synthesis, and the MTS group facilitates the introduction of thiol groups into peptides for a variety of applications. FMOC-ARG(MTS)-OH is thus a multifunctional and significant chemical in peptide chemistry.

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  • 88743-97-9 Structure
  • Basic information

    1. Product Name: FMOC-ARG(MTS)-OH
    2. Synonyms: FMOC-N-OMEGA-(MESITYLENE-2-SULFONYL)-L-ARGININE;FMOC-ARG(MTS)-OH;N-ALPHA-(9-FLUORENYLMETHOXYCARBONYL)-N-OMEGA-MESITYLENE SULFONYL-L-ARGININE;N-ALPHA-FMOC-N-OMEGA-(MESITYLENE-2-SULFONYL)-L-ARGININE;N-ALPHA-FMOC-N-G-(MESITYLENE-2-SULFONYL)-L-ARGININE;Nα-Fmoc-Nω-(mesitylene-2-sulfonyl)-L-arginine ;nα-fmoc-nω-(mesitylene-2-sulfonyl)-l-arginine;(2S)-5-[[Amino-[(2,4,6-trimethylphenyl)sulfonylamino]methylidene]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid
    3. CAS NO:88743-97-9
    4. Molecular Formula: C30H34N4O6S
    5. Molecular Weight: 578.68
    6. EINECS: N/A
    7. Product Categories: Fmoc-Amino Acids and Derivatives;Fmoc-Amino acid series
    8. Mol File: 88743-97-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.35g/cm3
    6. Refractive Index: 1.644
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. BRN: 7787250
    10. CAS DataBase Reference: FMOC-ARG(MTS)-OH(CAS DataBase Reference)
    11. NIST Chemistry Reference: FMOC-ARG(MTS)-OH(88743-97-9)
    12. EPA Substance Registry System: FMOC-ARG(MTS)-OH(88743-97-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: 22-24/25
    4. WGK Germany: 3
    5. RTECS:
    6. F: 10
    7. HazardClass: IRRITANT
    8. PackingGroup: N/A
    9. Hazardous Substances Data: 88743-97-9(Hazardous Substances Data)

88743-97-9 Usage

Uses

Used in Pharmaceutical and Biochemical Research:
FMOC-ARG(MTS)-OH is used as a building block in the synthesis of peptides for research purposes, allowing scientists to create and study novel peptide sequences with potential therapeutic or diagnostic applications.
Used in Peptide Drug Development:
In the pharmaceutical industry, FMOC-ARG(MTS)-OH is utilized as a component in the development of peptide-based drugs, where its properties can contribute to the stability, solubility, or activity of the final drug product.
Used in Chemical Synthesis for Specialty Applications:
FMOC-ARG(MTS)-OH is employed as a reagent in the synthesis of specialty chemicals, where its unique properties can be leveraged to create compounds with specific functions in various industrial applications.
Used in the Development of Bioconjugates:
FMOC-ARG(MTS)-OH is used as a precursor in the creation of bioconjugates, where the thiol-reactive MTS group can be used to attach peptides to other biomolecules, such as antibodies or nanoparticles, for applications in targeted drug delivery or biosensing.
Used in Solid-Phase Peptide Synthesis (SPPS):
In the field of peptide synthesis, FMOC-ARG(MTS)-OH is used as a protected amino acid in SPPS, where the FMOC group protects the amino acid's side chain during the stepwise assembly of the peptide chain, ensuring the correct sequence and preventing unwanted side reactions.

Check Digit Verification of cas no

The CAS Registry Mumber 88743-97-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,8,7,4 and 3 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 88743-97:
(7*8)+(6*8)+(5*7)+(4*4)+(3*3)+(2*9)+(1*7)=189
189 % 10 = 9
So 88743-97-9 is a valid CAS Registry Number.
InChI:InChI=1/C30H34N4O6S/c1-18-15-19(2)27(20(3)16-18)41(38,39)34-29(31)32-14-8-13-26(28(35)36)33-30(37)40-17-25-23-11-6-4-9-21(23)22-10-5-7-12-24(22)25/h4-7,9-12,15-16,25-26H,8,13-14,17H2,1-3H3,(H,33,37)(H,35,36)(H3,31,32,34)/t26-/m0/s1

88743-97-9 Well-known Company Product Price

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  • Aldrich

  • (47573)  Fmoc-Arg(Mts)-OH  ≥96.0% (HPLC)

  • 88743-97-9

  • 47573-5G-F

  • 4,662.45CNY

  • Detail

88743-97-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name (2S)-5-[[amino-[(2,4,6-trimethylphenyl)sulfonylamino]methylidene]amino]-2-(9H-fluoren-9-ylmethoxycarbonylamino)pentanoic acid

1.2 Other means of identification

Product number -
Other names Fmoc-Arg(Mts)-OH

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:88743-97-9 SDS

88743-97-9Upstream product

88743-97-9Downstream Products

88743-97-9Relevant articles and documents

Multicatalytic protease inhibitors

-

, (2008/06/13)

Disclosed herein are inhibitors of the multicatalytic protease enzyme which are represented by the general formula: STR1 Constituent members and preferred constituent members are disclosed herein. Methodologies for making and using the disclosed compounds are also set forth herein.

MULTICATALYTIC PROTEASE INHIBITORS

-

, (2008/06/13)

Disclosed herein are inbibitors of the multicatalytic protease enzyme which are represented by the general formula: STR1 Constituent members and preferred constituent members are disclosed herein. Methodologies for making and using the disclosed compounds are also set forth herein.

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