88929-43-5

Basic information

• Product Name: dihydroheptaprenol
• Synonyms: dihydroheptaprenol;3,7,11,15,19,23,27-Heptamethyl-6,10,14,18,22,26-octacosahexen-1-ol
• CAS NO: 88929-43-5
• Molecular Formula: C35H60O
• Molecular Weight: 496.858
• Mol File: 88929-43-5.mol

Chemical Properties

• Boiling Point: 581.9°C at 760 mmHg
• Flash Point: 136.1°C
• Appearance: /
• Density: 0.879g/cm³
• Vapor Pressure: 5.77E-16mmHg at 25°C
• Refractive Index: 1.496
• CAS DataBase Reference: dihydroheptaprenol(CAS DataBase Reference)
• NIST Chemistry Reference: dihydroheptaprenol(88929-43-5)
• EPA Substance Registry System: dihydroheptaprenol(88929-43-5)

Safety Data

• Hazardous Substances Data: 88929-43-5(Hazardous Substances Data)

Usage

InChI:InChI=1/C35H60O/c1-29(2)15-9-16-30(3)17-10-18-31(4)19-11-20-32(5)21-12-22-33(6)23-13-24-34(7)25-14-26-35(8)27-28-36/h15,17,19,21,23,25,35-36H,9-14,16,18,20,22,24,26-28H2,1-8H3/b30-17+,31-19+,32-21+,33-23+,34-25+

Upstream product

• 112766-68-4 (6Z,10Z,14E,18E,22E)-(R)-4-Benzenesulfonyl-3,7,11,15,19,23,27-heptamethyl-octacosa-6,10,14,18,22,26-hexaen-1-ol 
• 112766-68-4 (+/-)-4-phenylsulfonyl-3,7,11,15,19,23,27-heptamethyloctaeicosa-6Z,10Z,14E,18E,22E,26-hexaen-1-ol 
• 60012-69-3 4-Benzenesulphonyl-3-methylbutan-1-ol 
• 67517-13-9 phenylsulfonyl-1 methyl-2 butene-2 ol-4 Z 
• 90695-03-7 3,7,11,15,19,23-hexamethyltetraeicosa-2Z,6Z,10E,14E,18E,22-hexaen-1-ol 
• 77850-96-5 (6E,10E)-geranylgeranyl bromide 
• 58846-22-3 3,7,11,15,19-pentamethyleicosa-2Z,6E,10E,14E,18-pentaen-1-ol 
• 90695-01-5 (2Z,6E,10E,14E)-1-Bromo-3,7,11,15,19-pentamethyl-icosa-2,6,10,14,18-pentaene 
• 90695-02-6 (2Z,6Z,10E,14E,18E)-1-Bromo-3,7,11,15,19,23-hexamethyl-tetracosa-2,6,10,14,18,22-hexaene 
• 112792-38-8 4-phenylsulfonyl-3,7,11,15,19-pentamethyleicosa-2Z,6E,10E,14E,18-pentaen-1-ol 
• 112766-67-3 4-phenylsulfonyl-3,7,11,15,19,23-hexamethyltetraeicosa-2Z,6Z,10E,14E,18E,22-hexaen-1-ol 

Relevant articles and documents

Solid-phase organic synthesis of polyisoprenoid alcohols with traceless sulfone linker

(Chemical Equation Presented) Solid-phase organic synthesis of polyprenols with a traceless sulfone linker is described. The polymerbound benezenesulfinate is first linked with the "tail" building blocks of isoprenyl chlorides via S-alkylation. With use of dimsyl anion as an appropriate base, the polymer-bound α-sulfonyl carbanion is generated and coupled with other "body" building blocks in an efficient manner. After repeated processes and a global palladium-catalyzed desulfonation with LiEt3BH as the reducing agent, the desired polyprenols with various chain lengths and geometrical configurations are obtained in 32-59% overall yields. The solid-phase synthesis offers the advantage in facile isolation of polyprenols without tedious operation or time-consuming purification.

SYNTHESIS OF DOLICHOL-TYPE (S)-HEXA- AND (S)-HEPTAPRENOLS

(R)-1-Phenylsulfonyl-2-methylbutan-4-ol has been used as starting material for the stepwise synthesis of the dolichol-related hexa- and heptaprenols (S)-3,7,11,15,19,23-hexymethyltetraicosa-6Z,10Z,14E,18E,22-pentaene1-ol and (S)-3,7,-11,15,19,23,27-heptamethyloctaicosa-6Z,10Z,14E,18E,22E,26-hexaen-1-ol.

β,γ-dihydropolyprenyl alcohol derivatives and pharmaceutical composition containing a polyprenyl compound

A β,γ-dihydropolyprenyl alcohol derivative having the formula: STR1 wherein n is an integer of 5 to 7 and R is hydrogen, a lower alkyl group or an aliphatic or aromatic acyl group, is new and useful as a phylactic agent against human and animal infectious diseases. Other disclosed polyprenyl compounds are also useful as such agents.