889942-79-4

Basic information

• Product Name: 4-METHOXY-1H-INDOLE-3-CARBONITRILE
• Synonyms: 4-METHOXY-1H-INDOLE-3-CARBONITRILE;1H-Indole-3-carbonitrile, 4-Methoxy-
• CAS NO: 889942-79-4
• Molecular Formula: C10H8 N2 O
• Molecular Weight: 172.18
• Mol File: 889942-79-4.mol

Chemical Properties

• Appearance: /
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 4-METHOXY-1H-INDOLE-3-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-METHOXY-1H-INDOLE-3-CARBONITRILE(889942-79-4)
• EPA Substance Registry System: 4-METHOXY-1H-INDOLE-3-CARBONITRILE(889942-79-4)

Safety Data

• Hazardous Substances Data: 889942-79-4(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-METHOXY-1H-INDOLE-3-CARBONITRILE is used as an intermediate in the synthesis of bioactive molecules for the development of potential pharmaceuticals. Its unique chemical structure allows for the creation of various compounds with therapeutic properties.
Used in Organic Synthesis:
4-METHOXY-1H-INDOLE-3-CARBONITRILE is used as a key component in organic synthesis, enabling the production of a wide range of chemical compounds with diverse applications.
Used in Antidepressant and Anxiolytic Research:
4-METHOXY-1H-INDOLE-3-CARBONITRILE is used as a subject of research for its potential antidepressant and anxiolytic properties, with the aim of developing new treatments for mental health disorders.

Upstream product

• 1261025-52-8 4'-methoxyindole-3'-carboxaldehyde oxime 

Relevant articles and documents

Divergent reactivity of an indole glucosinolate yields Lossen or Neber rearrangement products: The phytoalexin rapalexin A or a unique β-d-glucopyranose fused heterocycle

Transformation of 1-t-Boc-4-methoxyindole-3-glucosinolate under acidic conditions yielded the potent phytoalexin rapalexin A, providing its first biomimetic synthesis via Lossen type rearrangement, while a novel 1-thioimidocarbonyl-β-d-glucopyranose heterocyclic system was obtained under basic conditions via Neber type rearrangement.

The first isocyanide of plant origin expands functional group diversity in cruciferous phytoalexins: Synthesis, structure and bioactivity of isocyalexin A

Although isocyanides are not rare amongst terrestrial microbes and marine organisms, despite tens of thousands of natural products isolated from plants, isocyanides are still missing. Isocyalexin A is the first isocyanide of plant origin. Isocyalexin A was isolated from UV-irradiated rutabaga roots and shown to be a new cruciferous phytoalexin. Its chemical structure was proven by analysis of NMR spectroscopic data and chemical synthesis.