889949-44-4

Basic information

• Product Name: [1-(2-AMINO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: [1-(2-AMINO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER;tert-Butyl [1-(2-aminophenyl)ethyl]carbamate;2-{1-[(tert-Butoxycarbonyl)amino]ethyl}aniline
• CAS NO: 889949-44-4
• Molecular Formula: C13H20N2O2
• Molecular Weight: 236.31
• Product Categories: pharmacetical
• Mol File: 889949-44-4.mol

Chemical Properties

• Boiling Point: 385.7°C at 760 mmHg
• Flash Point: 187.1°C
• Appearance: /
• Density: 1.073g/cm³
• Vapor Pressure: 3.74E-06mmHg at 25°C
• Refractive Index: 1.534
• PKA: 11.97±0.46(Predicted)
• CAS DataBase Reference: [1-(2-AMINO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: [1-(2-AMINO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER(889949-44-4)
• EPA Substance Registry System: [1-(2-AMINO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER(889949-44-4)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 889949-44-4(Hazardous Substances Data)

Usage

Uses

Used in Organic Synthesis:
[1-(2-AMINO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER is used as a building block for the synthesis of various organic molecules due to its unique structural features and reactivity.
Used in Pharmaceutical Industry:
[1-(2-AMINO-PHENYL)-ETHYL]-CARBAMIC ACID TERT-BUTYL ESTER is used as a key intermediate in the development of certain pharmaceuticals and drugs, leveraging its specific structural attributes to enhance drug properties and effectiveness.

InChI:InChI=1/C13H20N2O2/c1-9(10-7-5-6-8-11(10)14)15-12(16)17-13(2,3)4/h5-9H,14H2,1-4H3,(H,15,16)

Relevant articles and documents

Aniline derivatives possessing an inhibitory effect of nitric oxide synthase

Compounds represented by the general formula (1): ? (where R1is SR6or NR7R8, where R6is typically an alkyl group having 1-6 carbon atoms, R7is a hydrogen atom, an alkyl group having 1-6 carbon atoms or a nitro group, and R8is a hydrogen atom or an alkyl group having 1-6 carbon atoms; R2and R3are each typically a hydrogen atom or an alkyl group having 1-6 carbon atoms; R4is a hydrogen atom, an alkyl group having 1-6 carbon atoms or an amidino group of which the amine portion may be substituted by an alkyl or nitro group; R5is a hydrogen atom or an alkyl group having 1-6 carbon atoms; Y1, Y2, Y3and Y4which may be the same or different are each typically a hydrogen atom, a halogen atom or an alkoxy group having 1-6 carbon atoms; n and m are each an integer of 0 or 1), or possible stereoisomers or optically active forms of the compounds or pharmaceutically acceptable salts thereof. The compounds possess a potent nitric oxide synthase inhibiting activity and are useful as therapeutics of cerebrovascular diseases.

Selective neuronal nitric oxide synthase inhibitors

Peptidomimetic compositions for selective inhibition of neuronal nitric oxide synthase.