SYNTHESIS AND ANTIMALARIAL ACTIVITY OF N1-ISONICOTINOYL-3-METHYL-5-PHENYL-4-(SULFAMOYLPHENYLAZO)-1,2-DIAZOLES
A novel series of N1-isonicotinoyl-3-methyl-5-phenyl-4-(sulfamoylphenylazo)-1,2-diazoles have been synthesized by the condensation of sulfamoylphenylazo-1-phenyl-1,3-butanedione with isonicotinic acid hydrazide, using glacial acetic acid as condensing agent.Some of the products showed significant antimalarial activity against Plasmodium berghei KBG 173 in swiss mice.
Singh, C. P.
p. 57 - 62
(2007/10/02)
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