HETEROAROMATIC ARYL TRIAZOLE DERIVATIVES AS PDE10A ENZYME INHIBITORS
This invention is directed to compounds (Formula 1), which are PDE10A enzyme inhibitors. The invention provides a pharmaceutical composition comprising a therapeutically effective amount of a compound of the invention and a pharmaceutically acceptable car
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Page/Page column 38-39
(2011/07/07)
3-Phenyl-1,2,4-triazole-5-carbaldehydes Substituted in Position 1
The aldehydes 7 - first examples of the yet unknown class of 1,2,4-triazole-5-carbaldehydes substituted in position 1 - can be obtained in excellent yield by lead tetraacetate oxidation of 2; the Kroehnke reaction with 5 provides an alternative route.Due
Moderhack, Dietrich
p. 48 - 65
(2007/10/02)
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