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89494-39-3

2'-TBDMS-ibu-rG is a modified guanosine molecule with a tert-butyldimethylsilyl (TBDMS) group at the 2' position and an isobutyryl (ibu) group attached to the ribose ring. 2'-TBDMS-ibu-rG is commonly used in organic synthesis and nucleic acid research as a building block for various nucleotides and nucleic acid analogs. The TBDMS and isobutyryl groups provide protection to the guanosine molecule, allowing for easier manipulation and incorporation into larger structures.

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  • 89494-39-3 Structure

  • Basic information

    1. Product Name: 2'-TBDMS-ibu-rG
    2. Synonyms: 2'-TBDMS-ibu-rG;5'-O-[(1,1-Dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)guanosine;Guanosine,5'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-
    3. CAS NO:89494-39-3
    4. Molecular Formula: C20H33N5O6Si
    5. Molecular Weight: 467.59
    6. EINECS: -0
    7. Product Categories: N/A
    8. Mol File: 89494-39-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 2'-TBDMS-ibu-rG(CAS DataBase Reference)
    10. NIST Chemistry Reference: 2'-TBDMS-ibu-rG(89494-39-3)
    11. EPA Substance Registry System: 2'-TBDMS-ibu-rG(89494-39-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 89494-39-3(Hazardous Substances Data)

89494-39-3 Usage

Uses

Used in Organic Synthesis:
2'-TBDMS-ibu-rG is used as a building block for the synthesis of various nucleotides and nucleic acid analogs, facilitating the development of new compounds with potential applications in various fields.
Used in Nucleic Acid Research:
2'-TBDMS-ibu-rG is used as a protected guanosine derivative in nucleic acid research, enabling the study of its interactions with other molecules and its role in the structure and function of nucleic acids.
Used in RNA Modification:
2'-TBDMS-ibu-rG is used as a component in the development of modified RNA molecules, which can have improved stability, specificity, and functionality compared to unmodified RNA.
Used in Pharmaceutical Development:
2'-TBDMS-ibu-rG is used in the development of new pharmaceuticals, as its unique structure and properties may contribute to the design of novel therapeutic agents with improved efficacy and safety profiles.

Check Digit Verification of cas no

The CAS Registry Mumber 89494-39-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,4,9 and 4 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 89494-39:
(7*8)+(6*9)+(5*4)+(4*9)+(3*4)+(2*3)+(1*9)=193
193 % 10 = 3
So 89494-39-3 is a valid CAS Registry Number.

89494-39-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2'-TBDMS-ibu-rG

1.2 Other means of identification

Product number -
Other names Guanosine,5'-O-[(1,1-dimethylethyl)dimethylsilyl]-N-(2-methyl-1-oxopropyl)-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:89494-39-3 SDS

89494-39-3Relevant articles and documents

Nucleotides, XVIII. Synthesis and Properties of (tert-Butyldimethylsilyl)guanosines, Guanosine-3'-Phosphotriesters and Guanosine-containing Oligonucleotides

Flockerzi, Dieter,Schlosser, Wilhelm,Pfleiderer, Wolfgang

, p. 2069 - 2085 (2007/10/02)

Silylation of N2-benzoyl- (1) and N2-isobutyrylguanosin (2) by tert-butyldimethylsilyl chloride led to the various mono-, di- and tri-O-tert-butyldimethylsilyl derivatives 3-15.The synthesis of 2'- (24-31) and 3'-phosphotriesters (16

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