cas 89599-01-9, 3-BROMOBENZENESULFONAMIDE | Articles data ｜lookchem

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89599-01-9

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Chemoselective Cleavage of Acylsulfonamides and Sulfonamides by Aluminum Halides
The chemoselective cleavage of C-N bonds of amides, sulfonamides, and acylsulfonamides by aluminum halides is described. AlCl3and AlI3display complementary reactivities toward N-alkyl and N-acyl moieties. N-Alkylacylsulfonamides, sec
Sang, Dayong,Dong, Bingqian,Liu, Yunfeng,Tian, Juan
p. 3586 - 3595
(2022/02/25)

NOVEL N-ACYL-ARYLSULFONAMIDE DERIVATIVES AS AMINOACYL-TRNA SYNTHETASE INHIBITORS
The present invention relates to novel N-acyl-diarysulfonamides acting as inhibitors of bacterial aminoacyl-tRNA synthetase. These can be used as medicines or as constituent of medicines for the treatment of bacterial infections.
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Page/Page column 18; 19

(2016/09/22)

Design and synthesis of triazolopyrimidine acylsulfonamides as novel anti-mycobacterial leads acting through inhibition of acetohydroxyacid synthase
Novel triazolopyrimidine acylsulfonamides class of antimycobacterial agents, which are mycobacterial acetohydroxyacid synthase (AHAS) inhibitors were designed by hybridization of known AHAS inhibitors such as sulfonyl urea and triazolopyrimidine sulfonamides. This Letter describes the synthesis and SAR studies of this class of molecules by variation of two parts of the molecule, the phenyl and triazolopyrimidine rings. SAR study describes optimisation of enzyme potency, whole cell potency and evidence of mechanism of action.
Patil, Vikas,Kale, Manoj,Raichurkar, Anandkumar,Bhaskar, Brahatheeswaran,Prahlad, Dwarakanath,Balganesh, Meenakshi,Nandan, Santosh,Shahul Hameed
supporting information
p. 2222 - 2225
(2014/05/06)

Design and synthesis of benzenesulfonamide derivatives as potent anti-influenza hemagglutinin inhibitors
Structural optimization of salicylamide-based hemagglutinin (HA) inhibitor 1 resulted in the identification of cis-3-(5-hydroxy-1,3,3- trimethylcyclohexylmethylamino)benzenesulfonamide 28 and its derivatives as potent anti-influenza agents. The lead compo
Tang, Guozhi,Lin, Xianfeng,Qiu, Zongxing,Li, Wentao,Zhu, Lei,Wang, Lisha,Li, Shaohua,Li, Haodong,Lin, Wenbin,Yang, Mei,Guo, Tao,Chen, Li,Lee, Daniel,Wu, Jim Z.,Yang, Wengang
supporting information; experimental part
p. 603 - 607
(2011/10/09)

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Chemical Properties

Appearance/Colour :white powder
Melting Point: 151-156 °C(lit.)
Boiling Point: 375.8 °C at 760 mmHg
Flash Point:181.1 °C
Density: 1.754 g/cm³
Storage Temp.:Sealed in dry,Room Temperature
PKA: 9.81±0.60(Predicted)
PSA: 68.54000
LogP: 2.87760

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