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Ethyl 5-chloro-4-nitrothiophene-2-carboxylate is a chemical compound characterized by its molecular formula C9H6ClNO4S. It is a thiophene derivative that features a nitro group, a chloro group, and an ester functional group. Ethyl 5-chloro-4-nitrothiophene-2-carboxylate is recognized for its versatile reactivity and is a valuable asset in the realm of organic chemistry due to its ability to participate in a wide range of chemical reactions.

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  • 89640-03-9 Structure
  • Basic information

    1. Product Name: Ethyl 5-chloro-4-nitrothiophene-2-carboxylate
    2. Synonyms: 2-Thiophenecarboxylic acid, 5-chloro-4-nitro-, ethyl ester
    3. CAS NO:89640-03-9
    4. Molecular Formula: C7H6ClNO4S
    5. Molecular Weight: 235.65
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 89640-03-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
    8. Solubility: N/A
    9. CAS DataBase Reference: Ethyl 5-chloro-4-nitrothiophene-2-carboxylate(CAS DataBase Reference)
    10. NIST Chemistry Reference: Ethyl 5-chloro-4-nitrothiophene-2-carboxylate(89640-03-9)
    11. EPA Substance Registry System: Ethyl 5-chloro-4-nitrothiophene-2-carboxylate(89640-03-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 89640-03-9(Hazardous Substances Data)

89640-03-9 Usage

Uses

Used in Organic Synthesis:
Ethyl 5-chloro-4-nitrothiophene-2-carboxylate is utilized as a building block in the synthesis of various pharmaceuticals, agrochemicals, and other fine chemicals. Its presence in these industries is due to its ability to serve as a key intermediate in the production of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, Ethyl 5-chloro-4-nitrothiophene-2-carboxylate is used as a precursor for the development of new drugs. Its unique structure and reactivity allow it to be a component in the synthesis of molecules with potential therapeutic applications.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, Ethyl 5-chloro-4-nitrothiophene-2-carboxylate is employed as an intermediate for the synthesis of various agrochemicals, contributing to the development of products used in agriculture for pest control and crop protection.
Used in the Production of Other Complex Organic Molecules:
Ethyl 5-chloro-4-nitrothiophene-2-carboxylate is also used in the synthesis of other complex organic molecules, highlighting its role as a versatile intermediate in organic chemistry. Its capacity to undergo multiple chemical reactions makes it indispensable for creating a variety of specialized compounds.

Check Digit Verification of cas no

The CAS Registry Mumber 89640-03-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,6,4 and 0 respectively; the second part has 2 digits, 0 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 89640-03:
(7*8)+(6*9)+(5*6)+(4*4)+(3*0)+(2*0)+(1*3)=159
159 % 10 = 9
So 89640-03-9 is a valid CAS Registry Number.

89640-03-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-chloro-4-nitro-thiophene-2-carboxylic acid ethyl ester

1.2 Other means of identification

Product number -
Other names ethyl 5-chloro-4-nitrothiophene-2-carboxylate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:89640-03-9 SDS

89640-03-9Relevant articles and documents

Design, synthesis, and biological evaluation of novel 3-(thiophen-2-ylthio)pyridine derivatives as potential multitarget anticancer agents

Xi, Jian-Jun,He, Ruo-Yu,Zhang, Jian-Kang,Cai, Zhao-Bin,Zhuang, Rang-Xiao,Zhao, Yan-Mei,Shao, Yi-Dan,Pan, Xu-Wang,Shi, Ting-Ting,Dong, Zuo-Jun,Liu, Shou-Rong,Kong, Li-Min

, (2019/08/01)

A series of novel 3-(thiophen-2-ylthio)pyridine derivatives as insulin-like growth factor 1 receptor (IGF-1R) inhibitors was?designed and synthesized. IGF-1R kinase inhibitory activities and cytotoxicities against HepG2 and WSU-DLCL2 cell lines were teste

ANTI-NEOPLASTIC COMPOUNDS, COMPOSITIONS AND METHODS

-

Page/Page column 43-44, (2010/11/03)

Disclosed are novel compounds which are useful as therapeutics, especially in anti-neoplastic therapy and in other therapeutic regimes where cysteine protease inhibition is implicated.

ANTI-VIRAL COMPOUNDS

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Page/Page column 126, (2008/12/08)

Compounds effective in inhibiting replication of Hepatitis C virus ( HCV ) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, coformulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.

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