Design, synthesis, and biological evaluation of chicoric acid analogs as inhibitors of HIV-1 integrase
A series of analogs of the potent HIV-1 integrase (HIV IN) inhibitor chicoric acid (CA) was designed with the intention of ameliorating some of the parent natural product's undesirable properties, in particular its toxicity, instability, and poor membrane
Charvat, Trevor T.,Lee, Deborah J.,Robinson, W. Edward,Chamberlin, A. Richard
p. 4552 - 4567
(2007/10/03)
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