- Synthesis of 2,2,5-Trisubstituted 2 H-Pyrroles and 2,3,5-Trisubstituted 1 H-Pyrroles by Ligand-Controlled Site-Selective Dearomative C2-Arylation and Direct C3-Arylation
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Palladium-catalyzed site-selective dearomative C2-arylation of 2,5-diaryl-1H-pyrroles with aryl chlorides was accomplished, and a series of 2,2,5-triaryl-2H-pyrroles were synthesized. In addition, the site selectivity of the reaction was switched by simply changing the ligand, and the direct C3-arylated 2,3,5-triaryl-1H-pyrroles were prepared. The obtained 2,2,5-triaryl-2H-pyrroles could be further transformed into 2,2,5,5-tetraarylpyrrolidines.
- Yamaguchi, Miyuki,Fujiwara, Sakiko,Manabe, Kei
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supporting information
p. 6972 - 6977
(2019/09/03)
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- Synthesis of Furan- and Pyrrole-Containing α-Oligothiophenes via 1,4-Diketones
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Cyclization of the 1,4-dithienyl-1,4-diketones (3) by acid catalyst furnished the α-thienylfurans, whereas condensation with ammonium acetate provided the α-thienylpyrroles.The 2,5-bisthiophene (5) similarly gave the first syntheses of 2,5-bisthiophene (12) and 2,5-bisthiophene (13).
- Chen, Liang-Huei,Wang, Chin-Yu,Luo, Thung-Mei H.
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p. 1393 - 1398
(2007/10/02)
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- A CONVENIENT ROUTE TO POLYTHIOPHENES
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The Michael addition of aldehydes to α,β-unsaturated ketones (or their Mannich base precursors) developed by Stetter1 has been applied to the synthesis of 1,4-diketones containing one or more thiophene rings.These diketones could be cyclized in high yields to terthienyls.
- Wynberg, Hans,Metselaar, Jan
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