89892-22-8 Usage
Uses
Used in Pharmaceutical Synthesis:
7-Bromoquinazoline is used as a key intermediate in the synthesis of various pharmaceuticals for its ability to enhance the biological activity and pharmacological properties of the resulting compounds.
Used in Agrochemical Development:
In the agrochemical industry, 7-Bromoquinazoline serves as a building block for the creation of new agrochemicals, contributing to the development of more effective and targeted pest control solutions.
Used in Antiviral Drug Development:
7-Bromoquinazoline is utilized as a potential antiviral agent, with ongoing research exploring its ability to inhibit viral replication and reduce the severity of viral infections.
Used in Anticancer Drug Research:
7-Bromoquinazoline is employed in the research and development of anticancer drugs, as its unique structure and reactivity may contribute to the discovery of novel compounds with potential antitumor activity.
Used in Organic Compound Preparation:
As a versatile building block, 7-Bromoquinazoline is used in the preparation of various organic compounds with biological and medicinal properties, further expanding its applications in the field of drug discovery and development.
Check Digit Verification of cas no
The CAS Registry Mumber 89892-22-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 8,9,8,9 and 2 respectively; the second part has 2 digits, 2 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 89892-22:
(7*8)+(6*9)+(5*8)+(4*9)+(3*2)+(2*2)+(1*2)=198
198 % 10 = 8
So 89892-22-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H5BrN2/c9-7-2-1-3-8-6(7)4-10-5-11-8/h1-5H
89892-22-8Relevant articles and documents
NOVEL JNK INHIBITORS
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Page/Page column 106, (2008/12/07)
Disclosed are compounds of the formula (I) wherein X is N or CH, and Y is N or CR5. Also disclosed are methods of treating JNK and ERK mediated diseases using the compounds of formula 1.0.
Bromination of isoquinoline, quinoline, quinazoline and quinoxaline in strong acid
Brown,Gouliaev
, p. 83 - 86 (2007/10/03)
Bromination of benzazines and benzodiazines most often gives a mixture of products. In this paper, we show that isoquinoline (1) may be regioselectively monobrominated in concentrated H2SO4 using NBS or in CF3SO3H using N,N′-dibromoisocyanuric acid (DBI) to give 5-bromoisoquinoline (2). The bromination was found to be highly sensitive to the choice of brominating agent, acid, temperature and concentration. Quinoline, quinazoline and quinoxaline may be brominated likewise, although with the strong regioselectivity reserved to isoquinoline.
