- Polymers with alkyl- or heteroalkyl -aryl backbone and pharmaceutical compositions incorporating same
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A biologically active polymeric compound comprising an alkylaryl or heteroalkylaryl backbone having about 5 to about 50 repeating aromatic ring-containing units and which, according to the computer program marketed as SYBYL version 5.2 running on a DEC VAX 11/750 computer, is capable of forming a linear backbone having a helical secondary structure, and wherein the maximum diameter of the helical structure, as measured by the alkylaryl or heteroalkylaryl backbone, is less than 3 times greater than the maximum diameter of the aryl group of the alkylaryl or heteroalkylaryl backbone.
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- (o-Hydroxyphenyl)methylphosphonic acids: Synthesis and Potentiometric Determinations of their pKa Values
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(o-Hydroxyphenyl)methylphosphonic acids are readily obtained from o-(bromomethyl)- or o-(hydroxymethyl)phenols and trialkyl phosphites.Subsequent hydrolysis leads to the corresponding phosphonic acids.For a series of such compounds, the pKa val
- Boehmer, Volker,Vogt, Walter,Chafaa, Salah,Meullemeestre, Jean,Schwing, Marie-Jose,Vierling, Francois
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p. 139 - 149
(2007/10/02)
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