Synthesis of 'difficult' peptides free of aspartimide and related products, using peptoid methodology
We developed an efficient, cost effective strategy for Fmoc-based solid phase synthesis of 'difficult' peptides and/or peptides containing Asp/Asn-Gly sequences, free of aspartimide and related products, using a peptoid methodology for the preparation of N-substituted glycines.
Zahariev, Sotir,Guarnaccia, Corrado,Pongor, Csaba I.,Quaroni, Luca,?ema?ar, Ma?a,Pongor, Sándor