90030-48-1

Basic information

• Product Name: SODIUM 3-METHOXY-3-OXOPROPANE-1-SULFINATE
• Synonyms: SODIUM 3-METHOXY-3-OXOPROPANE-1-SULFINATE;Sodium3-methyoxy-3-oxopropane-1-sulfinate;3-Sulfinopropanoic acid 1-methyl ester sodium salt;SMOPS;Sodium 1-methyl 3-sulfinopropanoate;Sodium 1-Methyl 3-Sulfinopropionate
• CAS NO: 90030-48-1
• Molecular Formula: C₄H₇O₄S*Na
• Molecular Weight: 174.15
• Product Categories: pharmacetical
• Mol File: 90030-48-1.mol

Chemical Properties

• Melting Point: 199-216°C (decomposition)
• Boiling Point: 334°Cat760mmHg
• Flash Point: 155.8°C
• Appearance: /
• Density: g/cm³
• Vapor Pressure: 2.52E-05mmHg at 25°C
• Storage Temp.: Inert atmosphere,Room Temperature
• CAS DataBase Reference: SODIUM 3-METHOXY-3-OXOPROPANE-1-SULFINATE(CAS DataBase Reference)
• NIST Chemistry Reference: SODIUM 3-METHOXY-3-OXOPROPANE-1-SULFINATE(90030-48-1)
• EPA Substance Registry System: SODIUM 3-METHOXY-3-OXOPROPANE-1-SULFINATE(90030-48-1)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• Hazardous Substances Data: 90030-48-1(Hazardous Substances Data)

Usage

Uses

Used in Chemical Synthesis:
SODIUM 3-METHOXY-3-OXOPROPANE-1-SULFINATE is used as a reagent for the conversion of aryl and benzyl halides to their corresponding sulfonimides under basic conditions. This conversion is essential in the synthesis of various organic compounds and pharmaceuticals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, SODIUM 3-METHOXY-3-OXOPROPANE-1-SULFINATE is used as a key intermediate in the synthesis of various drugs and drug candidates. Its ability to facilitate the conversion of aryl and benzyl halides to sulfonimides makes it a valuable component in the development of new medications.
Used in Research and Development:
SODIUM 3-METHOXY-3-OXOPROPANE-1-SULFINATE is also utilized in research and development laboratories for the exploration of new chemical reactions and the synthesis of novel compounds. Its versatility as a reagent allows researchers to investigate a wide range of chemical transformations and applications.

InChI:InChI=1/C4H8O4S.Na/c1-8-4(5)2-3-9(6)7;/h2-3H2,1H3,(H,6,7);/q;+1/p-1

Upstream product

• 502635-00-9 methyl 3-[(3-oxobutyl)sulfonyl]propanoate 
• 15441-07-3 methyl 3-(chlorosulfonyl)propanoate 

Downstream Products

• 1001026-35-2 methyl 3-{[4-[[(tert-butyldimethylsilyl)oxy]methyl]benzyl]sulfonyl}propanoate 
• 1220026-02-7 3-[5-({[1-(4-fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carbonyl]-amino}-methyl)-pyridine-2-sulfonyl]-propionic acid methyl ester 
• 1270930-75-0 C₂₄H₂₇NO₅S₂ 
• 1295298-30-4 methyl 3-[5-(1-{[1-(4-fluorophenyl)-1H-pyrazolo[3,4-c]pyridine-4-carbonyl]amino}cyclopropyl)pyridine-2-sulfonyl]propionate 
• 85939-98-6 methyl 3-(methoxysulfinyl)propanoate 

Relevant articles and documents

Electrochemistry Enabled Nickel-Catalyzed Selective C?S Bond Coupling Reaction

This work describes an electrochemical enabled nickel-catalyzed chemoselective C?S bond coupling protocol for the production of aryl sulfides and sulfones. By simply switching the nickel catalysts and electrodes, this electrochemical C?S bond coupling has demonstrated excellent redox activity, scalability and sustainability. Furthermore, the mechanism for this electrochemical cross-coupling reaction has been investigated.

Cu-Catalyzed Deoxygenative C2-Sulfonylation Reaction of Quinoline N-Oxides with Sodium Sulfinate

An unexpected Cu-catalyzed deoxygenative C2-sulfonylation reaction of quinoline N-oxides in the presence of radical initiator K2S2O8 was developed that used sodium sulfinate as a sulfonyl coupling partner. The mechanism studies indicate that the reaction proceeds via Minisci-like radical coupling step to give sulfonylated quinoline with good chemical yields.

NOVEL HERBICIDES

Compounds of formula (I) wherein the substituents are defined as in claim 1, are suitable for use as herbicides. Also claimed is the intermediate (II) wherein R1 is chloro, R2 is hydrogen and XA is methylsulfonate, three p

A mild, convenient synthesis of sulfinic acid salts and sulfonamides from alkyl and aryl halides

A general, mild, and convenient method has been developed for the synthesis of various alkyl and aryl sulfinic acid salts and sulfonamides from the corresponding halides. Key to the success of this methodology is the design and facile synthesis of sodium 3-methoxy-3-oxopropane-1-sulfinate (SMOPS), a reagent that serves to introduce the protected sulfinate moiety directly to the substrate, thus avoiding the use of oxidizing and other harsh reaction conditions such as organolithium or Grignard reagents. Many functional groups, as well as heterocycles, are tolerated in the sequence.