Convenient preparation of aryl-substituted nortropanes by Suzuki-Miyaura methodology
The synthesis of a new bicyclic vinyl boronate (5) was accomplished from N-Boc-nortropinone (6) in two steps. The Suzuki-Miyaura coupling of 5 to a variety of aryl bromides and triflates afforded 3-aryl-8-azabicyclo[3.2.1]oct-2- enes in good yields by adj
Ghosh, Shyamali,Kinney, William A.,Gauthier, Diane A.,Lawson, Edward C.,Hudlicky, Tomas,Maryanoff, Bruce E.
p. 555 - 560
(2007/10/03)
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