- Synthesis, anticancer and antimicrobiological activities of pyrrolo[2,3-d]pyrimidines
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Reactions of 6-amino-3,4-dihydro-2-methoxy-4-oxopyrimidine 1a and its 3-methyl derivative 1b with chloroacetaldehyde and chloroacetyl chloride are discussed in this paper. Amongst others compounds, we have obtained, in low yield, the novel ring system oxazolo[3,2-c]pyrrolo[3,2-e]pyrimidine. The anticancer and anti-microbial activities of some of the obtained products are described.
- Quijano,Nogueras,Sanchez,Alvarez de Cienfuegos,Melgarejo
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p. 1079 - 1083
(2007/10/02)
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