90224-71-8

Basic information

• Product Name: 8-Bromo-7-quinolinol
• Synonyms: 8-Bromo-7-quinolinol;7-Hydroxy-8-bromo-quinoline;8-broMoquinolin-7-ol;8-Bromo-7-hydroxyquinoline
• CAS NO: 90224-71-8
• Molecular Formula: C₉H₆BrNO
• Molecular Weight: 224.05
• EINECS: -0
• Mol File: 90224-71-8.mol

Chemical Properties

• Melting Point: 196-198℃
• Appearance: /
• Density: 1.705
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 8-Bromo-7-quinolinol(CAS DataBase Reference)
• NIST Chemistry Reference: 8-Bromo-7-quinolinol(90224-71-8)
• EPA Substance Registry System: 8-Bromo-7-quinolinol(90224-71-8)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-37-60
• Hazardous Substances Data: 90224-71-8(Hazardous Substances Data)

Usage

Uses

Used in Dye Industry:
8-Bromo-7-quinolinol is used as a dye intermediate for the production of various dyes. Its unique molecular structure contributes to the color and stability of the dyes, making it a valuable component in this industry.
Used in Pharmaceutical Industry:
8-Bromo-7-quinolinol is used as an active pharmaceutical ingredient for the development of certain medications. Its chemical properties allow it to be incorporated into drug formulations, potentially offering therapeutic benefits.
Safety Precautions:
It is important to handle 8-Bromo-7-quinolinol with care, as it can cause harm if exposed to the skin or if inhaled. Additionally, it can be harmful to aquatic life, so proper disposal and containment measures should be taken to minimize environmental impact.

InChI:InChI=1S/C9H6BrNO/c10-8-7(12)4-3-6-2-1-5-11-9(6)8/h1-5,12H

Upstream product

• 580-20-1 quinolin-7-ol 

Downstream Products

• 33494-81-4 phosphoric acid di-tert-butyl ester 

Relevant articles and documents

Acylhydrazone Subunits as a Proton Cargo Delivery System in 7-Hydroxyquinoline

The reimagined concept of long-range tautomeric proton transfer using crane subunits is shown by designing and synthesising two new acylhydrazones containing a 7-hydroxyquinoline (7-OHQ) platform. The acylhydrazone subunits attached to the 7-OHQ at the 8t

A Dearomatization/Debromination Strategy for the [4+1] Spiroannulation of Bromophenols with α,β-Unsaturated Imines

A novel [4+1] spiroannulation of o- & p-bromophenols with α,β-unsaturated imines has been developed for the direct synthesis of a new family of azaspirocyclic molecules. Notably, several other halophenols (X=Cl, I) were also applicable for this transformation. Moreover, a catalytic asymmetric version of the reaction was realized with 1-bromo-2-naphthols by using a chiral ScIII/Py-Box catalyst. Mechanistic studies revealed that this domino reaction proceeded through electrophile-triggered dearomatization of phenol derivatives at their halogenated positions and followed by halogen-displacement with N-nucleophiles via a radical-based SRN1 mechanism.

MODULATORS OF CXCR7

Compounds having formula (I) or pharmaceutically acceptable salts, hydrates or N-oxides thereof are provided and are useful for binding to CXCR7, and treating diseases that are dependent, at least in part, on CXCR7 activity. Accordingly, the present inven