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8-Bromo-7-quinolinol, also known as 5-Chloro-8-hydroxyquinoline or 5-chlorooxine, is a specialized chemical compound characterized by the presence of bromine and quinolinol in its molecular structure. It is typically a light yellow crystalline powder and is known for its unique properties and characteristics.

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  • 90224-71-8 Structure
  • Basic information

    1. Product Name: 8-Bromo-7-quinolinol
    2. Synonyms: 8-Bromo-7-quinolinol;7-Hydroxy-8-bromo-quinoline;8-broMoquinolin-7-ol;8-Bromo-7-hydroxyquinoline
    3. CAS NO:90224-71-8
    4. Molecular Formula: C9H6BrNO
    5. Molecular Weight: 224.05
    6. EINECS: -0
    7. Product Categories: N/A
    8. Mol File: 90224-71-8.mol
  • Chemical Properties

    1. Melting Point: 196-198℃
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.705
    6. Refractive Index: N/A
    7. Storage Temp.: 2-8°C
    8. Solubility: N/A
    9. CAS DataBase Reference: 8-Bromo-7-quinolinol(CAS DataBase Reference)
    10. NIST Chemistry Reference: 8-Bromo-7-quinolinol(90224-71-8)
    11. EPA Substance Registry System: 8-Bromo-7-quinolinol(90224-71-8)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: 36/37/38
    3. Safety Statements: 26-37-60
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 90224-71-8(Hazardous Substances Data)

90224-71-8 Usage

Uses

Used in Dye Industry:
8-Bromo-7-quinolinol is used as a dye intermediate for the production of various dyes. Its unique molecular structure contributes to the color and stability of the dyes, making it a valuable component in this industry.
Used in Pharmaceutical Industry:
8-Bromo-7-quinolinol is used as an active pharmaceutical ingredient for the development of certain medications. Its chemical properties allow it to be incorporated into drug formulations, potentially offering therapeutic benefits.
Safety Precautions:
It is important to handle 8-Bromo-7-quinolinol with care, as it can cause harm if exposed to the skin or if inhaled. Additionally, it can be harmful to aquatic life, so proper disposal and containment measures should be taken to minimize environmental impact.

Check Digit Verification of cas no

The CAS Registry Mumber 90224-71-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,2,2 and 4 respectively; the second part has 2 digits, 7 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 90224-71:
(7*9)+(6*0)+(5*2)+(4*2)+(3*4)+(2*7)+(1*1)=108
108 % 10 = 8
So 90224-71-8 is a valid CAS Registry Number.
InChI:InChI=1S/C9H6BrNO/c10-8-7(12)4-3-6-2-1-5-11-9(6)8/h1-5,12H

90224-71-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-Bromo-7-quinolinol

1.2 Other means of identification

Product number -
Other names 8-bromo-1H-quinolin-7-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:90224-71-8 SDS

90224-71-8Upstream product

90224-71-8Downstream Products

90224-71-8Relevant articles and documents

Acylhydrazone Subunits as a Proton Cargo Delivery System in 7-Hydroxyquinoline

Antonov, Liudmil,Georgiev, Anton,Hirashima, Shin-ichi,Hori, Yutaro,Matsushima, Yasuyuki,Miura, Tsuyoshi,Nakashima, Kosuke,Petek, Anton,Yordanov, Dancho

supporting information, p. 11559 - 11566 (2021/07/16)

The reimagined concept of long-range tautomeric proton transfer using crane subunits is shown by designing and synthesising two new acylhydrazones containing a 7-hydroxyquinoline (7-OHQ) platform. The acylhydrazone subunits attached to the 7-OHQ at the 8t

A Dearomatization/Debromination Strategy for the [4+1] Spiroannulation of Bromophenols with α,β-Unsaturated Imines

Bai, Lu,Ge, Yicong,Hao, Jiamao,Liu, Jingjing,Luan, Xinjun,Qin, Cheng

supporting information, p. 18985 - 18989 (2020/08/26)

A novel [4+1] spiroannulation of o- & p-bromophenols with α,β-unsaturated imines has been developed for the direct synthesis of a new family of azaspirocyclic molecules. Notably, several other halophenols (X=Cl, I) were also applicable for this transformation. Moreover, a catalytic asymmetric version of the reaction was realized with 1-bromo-2-naphthols by using a chiral ScIII/Py-Box catalyst. Mechanistic studies revealed that this domino reaction proceeded through electrophile-triggered dearomatization of phenol derivatives at their halogenated positions and followed by halogen-displacement with N-nucleophiles via a radical-based SRN1 mechanism.

MODULATORS OF CXCR7

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Page/Page column 52-53, (2010/06/11)

Compounds having formula (I) or pharmaceutically acceptable salts, hydrates or N-oxides thereof are provided and are useful for binding to CXCR7, and treating diseases that are dependent, at least in part, on CXCR7 activity. Accordingly, the present inven

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