Synthesis and Antitumor Activity of Cyclophosphamide Analogues. 3. Preparation, Molecular Structure Determination, and Anticancer Screening of Racemic cis- and trans-4-Phenylcyclophosphamide
Cyclization of racemic 3-amino-3-phenyl-1-propanol with bis(2-chloroethyl)phosphoramidic dichloride gave a diastereomeric mixture of 4-phenylcyclophosphamide (3), which was chromatographically separated into the faster and slower eluting components.A comb
Boyd, Victoria L.,Zon, Gerald,Himes, Vicky L.,Stalick, Judith K.,Mighell, Alan D.,Secor, Henry V.
p. 372 - 375
(2007/10/02)
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