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CAS

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90566-53-3

Fluticasone is a synthetic corticosteroid that belongs to the class of glucocorticoids. It is a potent anti-inflammatory drug used for the management of various respiratory and inflammatory conditions.
Used in Pharmaceutical Industry:
Fluticasone is used as a therapeutic agent for the treatment of asthma and allergic rhinitis. It is available in the form of Flonase, a nasal spray that helps to relieve nasal congestion and inflammation caused by allergies.
Used in Respiratory Medicine:
Fluticasone is used as an inhaled corticosteroid for the treatment of respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma. It helps to reduce inflammation in the airways, improve lung function, and control symptoms.

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  • 90566-53-3 Structure

  • Basic information

    1. Product Name: Fluticasone
    2. Synonyms: (6s,9s,10s,11s,13s,14s,16r,17r)-6,9-difluoro-17-(fluoromethylsulfanylcarbonyl)-11,17-dihydroxy-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one;FLUTICASONE;FluticasonePropionate98.5%;Androsta-1,4-diene-17-carbothioic acid, 6,9-difluoro-11,17-dihydroxy-16-methyl-3-oxo-, S-(fluoromethyl) ester, (6.alpha.,11.beta.,16.alpha.,17.alpha.)-;6α,9-Difluoro-11β,17-dihydroxy-16α-methyl-3-oxoandrosta-1,4-diene-17β-carbothioic acid S-(fluoromethyl) ester;6α,9-Difluoro-16α-methyl-11β-hydroxy-17-hydroxy-3-oxoandrosta-1,4-diene-17β-carbothioic acid S-(fluoromethyl) ester;Fluticasone Dipropionate;Androsta-1,4-diene-17- Carbothioic acid, 6,9-difluoro- 11,17-dihydroxy-16-Methyl-3- oxo-, S-(fluoroMethyl) ester, (6α,11β,16α,17α)-
    3. CAS NO:90566-53-3
    4. Molecular Formula: C25H31F3O5S
    5. Molecular Weight: 500.57
    6. EINECS: N/A
    7. Product Categories: API
    8. Mol File: 90566-53-3.mol

  • Chemical Properties

    1. Melting Point: 237-239 °C
    2. Boiling Point: 553.2 °C at 760 mmHg
    3. Flash Point: 288.4 °C
    4. Appearance: /
    5. Density: 1.37 g/cm3
    6. Refractive Index: N/A
    7. Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
    8. Solubility: Acetonitrile (Slightly), Chloroform (Slightly)
    9. PKA: 11.66±0.70(Predicted)
    10. Stability: Hygroscopic, Unstable in Solution
    11. CAS DataBase Reference: Fluticasone(CAS DataBase Reference)
    12. NIST Chemistry Reference: Fluticasone(90566-53-3)
    13. EPA Substance Registry System: Fluticasone(90566-53-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 90566-53-3(Hazardous Substances Data)

90566-53-3 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 90566-53-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,5,6 and 6 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 90566-53:
(7*9)+(6*0)+(5*5)+(4*6)+(3*6)+(2*5)+(1*3)=143
143 % 10 = 3
So 90566-53-3 is a valid CAS Registry Number.
InChI:InChI=1/C22H27F3O4S/c1-11-6-13-14-8-16(24)15-7-12(26)4-5-19(15,2)21(14,25)17(27)9-20(13,3)22(11,29)18(28)30-10-23/h4-5,7,11,13-14,16-17,27,29H,6,8-10H2,1-3H3/t11-,13+,14?,16+,17+,19+,20+,21+,22+/m1/s1

90566-53-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name fluticasone

1.2 Other means of identification

Product number -
Other names Flutionum

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:90566-53-3 SDS

90566-53-3Relevant articles and documents

17.BETA- (ALPHA-HYDROXY) -ESTERS OF ANDROSTANES AS INTERMEDIATES FOR THE PREPARATION FOR THE PREPARATION OF 17Β-FLUORINATED-ANDROSTANE ESTERS

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Page 31-32, (2008/06/13)

Process for the preparation of polyhalogenated steroids, in particular of androstanic fluoro derivatives corticosteroids by means of the formation of new androstanic S-hydroxy alkyl or aralkyl-17-carbothioate intermediates.

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