906095-67-8

Basic information

• Product Name: 2-Amino-5-fluoro-3-iodo-benzoic acid methyl ester
• Synonyms: 2-Amino-5-fluoro-3-iodo-benzoic acid methyl ester;methyl 2-amino-5-fluoro-3-iodobenzoate
• CAS NO: 906095-67-8
• Molecular Formula: C₈H₇FINO₂
• Molecular Weight: 295.0495532
• Mol File: 906095-67-8.mol

Chemical Properties

• Boiling Point: 331.3±42.0 °C(Predicted)
• Appearance: /
• Density: 1.892±0.06 g/cm3(Predicted)
• PKA: 0.02±0.10(Predicted)
• CAS DataBase Reference: 2-Amino-5-fluoro-3-iodo-benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Amino-5-fluoro-3-iodo-benzoic acid methyl ester(906095-67-8)
• EPA Substance Registry System: 2-Amino-5-fluoro-3-iodo-benzoic acid methyl ester(906095-67-8)

Safety Data

• Hazardous Substances Data: 906095-67-8(Hazardous Substances Data)

Usage

Structure

Methyl ester derivative of 2-amino-5-fluoro-3-iodo-benzoic acid with fluoro and iodo substituents on the benzene ring

Potential applications

Organic synthesis, pharmaceutical research

Unique structural features

May confer beneficial properties for drug development

Functional groups

Valuable building blocks for synthesis of complex chemical compounds

Interest to researchers

Medicinal chemistry, drug discovery.

Upstream product

• 319-24-4 2-amino-5-fluoro-benzoic acid methyl ester 
• 516-12-1 N-iodo-succinimide 

Downstream Products

• 906095-68-9 methyl 2-amino-5-fluoro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate 

Relevant articles and documents

COMPOUND FOR USE IN RETINAL DISEASES

Provided is an aldehyde binder, specifically, disclosed is a compound as represented by formula (II) or a pharmaceutically acceptable salt.

PROTEIN KINASE MODULATORS

The invention relates in part to molecules having certain biological activities that include, but are not limited to, inhibiting cell proliferation, modulating protein kinase activity and modulating polymerase activity. Molecules of the invention can modulate Pim kinase activity and/or FMS-like tyrosine kinase (Flt) activity. The invention also relates in part to methods for using such molecules.

2-ALKYLBENZOXAZOLE CARBOXAMIDES AS 5HT3 MODULATORS

Compounds of formulae I and II: are disclosed as 5-HT3 inhibitors. Those compounds are useful in treating CINV, IBS-D and other diseases and conditions.

Benzoxazole carboxamides for treating CINV and IBS-D

Compounds of formulae I and II: are disclosed as 5-HT3 inhibitors. Those compounds that exhibit central activity are useful in treating CINV; those that inhibit peripheral receptors are useful to treat IBS-D.