- TLR2 MODULATOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS AND USES THEREOF
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The present disclosure relates to compounds which modulate the activity of Toll-like receptor (TLR) proteins, including agonists or activators, partial agonists, and antagonists. Of particular interest of compounds that modulate the activity of TLR2, as well as methods of using such compounds to treat cancer and other disorders associated with a TLR2 pathway.
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Paragraph 001481-001482
(2021/12/08)
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- FXR regulator with spirane structure
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The invention provides a new compound which has certain agonist activity on a Farnesoid X receptor (FXR) and is used for treating FXR mediated diseases and/or symptoms such as liver disease and gastrointestinal disease. (The formula is shown in the description.).
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- NITROGEN-CONTAINING HETEROCYCLIC COMPOUNDS AS FXR MODULATORS
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The present technology is directed to compounds, compositions, and methods related to modulation of FXR. In particular, the present compounds and compositions may be used to treat FXR-mediated disorders and conditions, including, e.g., liver disease, hype
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Paragraph 0112; 0113
(2018/05/24)
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