908267-63-0

Basic information

• Product Name: 4-bromo-2-isopropylpyridine
• Synonyms: 4-bromo-2-isopropylpyridine
• CAS NO: 908267-63-0
• Molecular Formula: C8H10BrN
• Molecular Weight: 200.0757
• Mol File: 908267-63-0.mol

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• CAS DataBase Reference: 4-bromo-2-isopropylpyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-2-isopropylpyridine(908267-63-0)
• EPA Substance Registry System: 4-bromo-2-isopropylpyridine(908267-63-0)

Safety Data

• Hazardous Substances Data: 908267-63-0(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
4-bromo-2-isopropylpyridine is utilized as a key intermediate in the synthesis of pharmaceutical drugs. Its unique structure allows for the development of new chemical entities that can address unmet medical needs and contribute to advancements in healthcare.
Used in Agrochemical Industry:
4-bromo-2-isopropylpyridine also serves as an important building block in the creation of agrochemicals, which are essential for enhancing crop protection and ensuring sustainable agricultural practices.
Used in Organic Synthesis:
4-bromo-2-isopropylpyridine is employed as a versatile reactant in organic synthesis reactions, enabling the production of a wide range of chemical compounds with diverse applications across various industries.

Upstream product

• 1120-87-2 4-bromopyridin 
• 75-30-9 2-iodo-propane 
• 1621222-28-3 phenyl 4-bromo-2-isopropylpyridine-1(2H)-carboxylate 

Downstream Products

• 1357476-67-5 4-bromo-2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridine 

Relevant articles and documents

Radical chain monoalkylation of pyridines

The monoalkylation of N-methoxypyridinium salts with alkyl radicals generated from alkenes (via hydroboration with catecholborane), alkyl iodides (via iodine atom transfer) and xanthates is reported. The reaction proceeds under neutral conditions since no acid is needed to activate the heterocycle and no external oxidant is required. A rate constant for the addition of a primary radical to N-methoxylepidinium >107 M-1 s-1 was experimentally determined. This rate constant is more than one order of magnitude larger than the one measured for the addition of primary alkyl radicals to protonated lepidine demonstrating the remarkable reactivity of methoxypyridinium salts towards radicals. The reaction has been used for the preparation of unique pyridinylated terpenoids and was extended to a three-component carbopyridinylation of electron-rich alkenes including enol esters, enol ethers and enamides.

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