cas 90871-40-2, 3-(benzylsulfanyl)-5-methyl-4H-1,2,4-triazol-4-amine

Articles about 90871-40-2Total 3 be found

Small-Molecule APOBEC3G DNA Cytosine Deaminase Inhibitors Based on a 4-Amino-1,2,4-triazole-3-thiol Scaffold
APOBEC3G (A3G) is a single-stranded DNA cytosine deaminase that functions in innate immunity against retroviruses and retrotransposons. Although A3G can potently restrict Vif-deficient HIV-1 replication by catalyzing excessive levels of G→A hypermutation,
Olson, Margaret E.,Li, Ming,Harris, Reuben S.,Harki, Daniel A.
p. 112 - 117
(2013/02/26)

Gas-phase pyrolysis of 4-amino-3-allylthio-1,2,4-triazoles: A new route to [1,3]thiazolo[3,2-b][1,2,4]triazoles
A short route to the [1,3]thiazolol[3,2-b]-[1,2,4]triazole ring system in moderate overall yield was provided by an unusual pyrolysis sequence. The carbon atoms in the fused triazole and thaizole rings were derived from a 4-aminotriazole-3-thione unit and allyl groups. Dry-flash chromatography was carried out on silica gel using a hexane-ethyl acetate gradient as eluent.
Cartwright, Dale D.J.,Clark, Bernard A.J.,McNab, Hamish
p. 424 - 428
(2007/10/03)

Solvation models in the reaction between benzyl bromide and s-triazole
The kinetics of nucleophilic substitution on benzyl bromide by s-triazole has been studied in different pure (protic and aprotic) solvents.The reaction is overall second order, with first order dependence on and the .The rate data is correlated with different solvent parameters using linear multiple regression analysis.From the regression coefficients, information on the solvent-reactant and the solvent-intermediate interactions is obtained and the solvation models are proposed.The reaction has also been studied at different temperatures and the thermodynamic parameters ΔH(excit.), ΔS(excit.) and ΔG(excit.) are computed.
Manikyamba, P
p. 959 - 962
(2007/10/02)