Straightforward methodology for the enantioselective synthesis of benzo[a]- and indolo[2,3-a]quinolizidines
(Chemical Equation Presented) An enantioselective two-step route to substituted benzo[a]- and indolo[2,3-a]quinolizidines has been developed. It consists of (i) a stereoselective cyclocondensation of a racemic or prochiral δ-oxo(di)ester with either (S)-(
Amat, Mercedes,Santos, Maria M. M.,Bassas, Oriol,Llor, Nuria,Escolano, Carmen,Gomez-Esque, Arantxa,Molins, Elies,Allin, Steven M.,McKee, Vickie,Bosch, Joan
p. 5193 - 5201
(2008/02/08)
Complementary routes for the stereoselective synthesis of functionalized benzoquinolizidine targets
We report new and complementary routes for the highly stereoselective construction of functionalized benzoquinolizidine targets from readily available, non-racemic chiral templates. The methods developed allow us to predetermine relative product stereoche
Allin, Steven M.,Duffy, Liam J.,Bulman Page, Philip C.,McKee, Vickie,Edgar, Mark,McKenzie, Michael J.,Amat, Mercedes,Bassas, Oriol,Santos, Maria M.M.,Bosch, Joan
p. 5713 - 5716
(2007/10/03)
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