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90954-53-3

ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2 is a peptide sequence that consists of 31 amino acids. It is a derivative of the calcitonin gene-related peptide (CGRP) and has vasodilatory properties. The presence of glycine (GLY) residues in the sequence contributes to its flexibility and stability.

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  • ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2

    Cas No: 90954-53-3

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  • ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2

    Cas No: 90954-53-3

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  • ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2

    Cas No: 90954-53-3

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  • Henan Allgreen Chemical Co.,Ltd
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  • 90954-53-3 Structure

  • Basic information

    1. Product Name: ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2
    2. Synonyms: ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2;ACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAF-NH2 (DISULFIDE BRIDGE: 2-7);CalcitoninGeneRelatedPeptidehuMan,CalcitoninGeneRelatedPeptidehuMa;Human calcitonin gene-related peptide 1;α-CGRP (human)|Calcitonin Gene Related Peptide II, human;ALPHA-CGRP (HUMAN);ALPHA-CGRP (HUMAN) TRIFLUOROACETATE SALT;ALPHA-CALCITONIN GENE RELATED PEPTIDE, HUMAN
    3. CAS NO:90954-53-3
    4. Molecular Formula: C163H267N51O49S2
    5. Molecular Weight: 3789.31
    6. EINECS: N/A
    7. Product Categories: Peptide;Calcitonin and CGRP receptor
    8. Mol File: 90954-53-3.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /powder
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: −20°C
    8. Solubility: N/A
    9. Water Solubility: Soluble in water or 1% acetic acid at 1mg/ml.
    10. CAS DataBase Reference: ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2(CAS DataBase Reference)
    11. NIST Chemistry Reference: ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2(90954-53-3)
    12. EPA Substance Registry System: ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2(90954-53-3)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany: 3
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 90954-53-3(Hazardous Substances Data)

90954-53-3 Usage

Uses

Used in Pharmaceutical Industry:
ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2 is used as a potent, long-lasting vasodilator for treating various cardiovascular conditions. Its vasodilatory effects help in reducing blood pressure and improving blood flow to tissues and organs.
Used in Diabetes Management:
ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2 is used as a therapeutic agent for diabetes management. The activation of CGRP receptors on pancreatic β-cells increases plasma levels of pancreatic enzymes, which aids in the regulation of blood sugar levels and improves insulin sensitivity.
Used in Neurological Disorders:
Due to its vasodilatory properties, ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2 can be used in the treatment of neurological disorders such as migraines. It helps in reducing the frequency and severity of migraine attacks by dilating blood vessels and improving blood flow to the brain.
Used in Cosmetic Industry:
The peptide sequence ALA-CYS-ASP-THR-ALA-THR-CYS-VAL-THR-HIS-ARG-LEU-ALA-GLY-LEU-LEU-SER-ARG-SER-GLY-GLY-VAL-VAL-LYS-ASN-ASN-PHE-VAL-PRO-THR-ASN-VAL-GLY-SER-LYS-ALA-PHE-NH2 can be used in cosmetic formulations for its potential anti-aging and skin rejuvenation properties. Its ability to improve blood flow and promote collagen synthesis can contribute to healthier and more youthful-looking skin.

Biochem/physiol Actions

Potent, long-lasting vasodilator; activation of CGRP receptors on pancreatic β-cells increases plasma levels of pancreatic enzymes.

Check Digit Verification of cas no

The CAS Registry Mumber 90954-53-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,0,9,5 and 4 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 90954-53:
(7*9)+(6*0)+(5*9)+(4*5)+(3*4)+(2*5)+(1*3)=153
153 % 10 = 3
So 90954-53-3 is a valid CAS Registry Number.
InChI:InChI=1/C163H269N51O49S2/c1-73(2)52-97(186-116(226)65-179-131(233)82(18)183-139(241)98(53-74(3)4)193-137(239)94(44-35-49-176-162(171)172)188-142(244)101(57-91-62-175-72-182-91)199-159(261)128(88(24)221)213-156(258)123(79(13)14)207-151(253)110(71-265)204-160(262)126(86(22)219)210-133(235)84(20)185-157(259)125(85(21)218)211-147(249)105(61-119(229)230)198-150(252)109(70-264)203-130(232)81(17)166)140(242)194-99(54-75(5)6)141(243)202-108(69-217)149(251)190-95(45-36-50-177-163(173)174)138(240)201-106(67-215)134(236)180-63-115(225)178-64-118(228)205-121(77(9)10)155(257)208-122(78(11)12)154(256)191-93(43-32-34-48-165)136(238)196-102(58-112(167)222)144(246)197-103(59-113(168)223)143(245)195-100(56-90-40-29-26-30-41-90)145(247)209-124(80(15)16)161(263)214-51-37-46-111(214)152(254)212-127(87(23)220)158(260)200-104(60-114(169)224)146(248)206-120(76(7)8)153(255)181-66-117(227)187-107(68-216)148(250)189-92(42-31-33-47-164)135(237)184-83(19)132(234)192-96(129(170)231)55-89-38-27-25-28-39-89/h25-30,38-41,62,72-88,92-111,120-

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