Towards the development of oxadiazinanones as chiral auxiliaries: synthesis and application of N3-haloacetyloxadiazinanones
Oxadiazinanones derived from (1R,2S)-ephedrine and (1R,2S)-norephedrine were employed in the asymmetric α-halo aldol reaction. The optimized yields and diastereoselectivities for the ephedrine based oxadiazinanone aldol reaction ranged from fair to good.
Hoover, Trisha R.,Groeper, Jonathan A.,Parrott II, Raleigh W.,Chandrashekar, Seshanand P.,Finefield, Jennifer M.,Dominguez, Alexandro,Hitchcock, Shawn R.
p. 1831 - 1841
(2007/10/03)
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