911417-24-8

Basic information

• Product Name: Phenol, 3-(4-chloro-2-quinazolinyl)-, 1-acetate
• Synonyms: Phenol, 3-(4-chloro-2-quinazolinyl)-, 1-acetate;3-(4-Chloroquinazolin-2-yl)phenyl acetate
• CAS NO: 911417-24-8
• Molecular Formula: C₁₆H₁₁ClN₂O₂
• Molecular Weight: 298.72374
• Mol File: 911417-24-8.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Phenol, 3-(4-chloro-2-quinazolinyl)-, 1-acetate(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 3-(4-chloro-2-quinazolinyl)-, 1-acetate(911417-24-8)
• EPA Substance Registry System: Phenol, 3-(4-chloro-2-quinazolinyl)-, 1-acetate(911417-24-8)

Safety Data

• Hazardous Substances Data: 911417-24-8(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
Phenol, 3-(4-chloro-2-quinazolinyl)-, 1-acetate is used as a therapeutic agent for the treatment of various diseases and conditions. Its potential medicinal properties are being studied, and further research is ongoing to explore its applications in medicine.

Upstream product

• 56071-04-6 2-(3-methoxyphenyl)quinazolin-4(3H)-one 
• 28144-70-9 anthranilic acid amide 
• 1711-05-3 m-anisoyl chloride 
• 911417-23-7 2-(3-hydroxylphenyl)quinazolin-4(3H)-one 
• 371947-93-2 3-(4-oxo-3,4-dihydroquinazolin-2-yl)phenyl acetate 

Downstream Products

• 911417-67-9 tert-butyl 5-(2-(3-(2-(2-(dimethylamino)-ethylamino)-2-oxoethoxy)phenyl)quinazolin-4-ylamino)-1H-indazole-1-carboxylate 
• 911417-61-3 tert-butyl 5-(2-(3-(2-tert-butoxy-2-oxoethoxy)phenyl)quinazolin-4-ylamino)-1H-indazole-1-carboxylate 
• 911417-95-3 tert-butyl 5-(2-(3-(2-(isopropylamino)-2-oxoethoxy)phenyl)quinazolin-4-ylainino)-1H-indazole-1-carboxylate 
• 1024582-76-0 tert-butyl 5-(2-(3-((1-methyl-1H-imidazol-2-yl)methoxy)-phenyl)quinazolin-4-ylamino)-1H-indazole-1-carboxylate 
• 1024582-75-9 tert-butyl 5-(2-(3-(oxazol-2-ylmethoxy)phenyl)-quinazolin-4-ylamino)-1H-indazole-1-carboxylate 
• 911417-69-1 tert-butyl 5-(2-(3-(2-isopropoxy-2-oxoethoxy)phenyl)quinazolin-4-ylamino)-1H-indazole-1-carboxylate 
• 911417-26-0 tert-butyl 5-(2-(3-hydroxyphenyl)-quinazolin-4-ylamino)-1H-indazole-1-carboxylate 
• 911417-62-4 2-(3-(4-(1H-indazol-5-ylamino)quinazolin-2-yl)phenoxy)acetic acid 
• 911417-87-3 2-[3-[4-(1H-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-N-propan-2-ylacetamide 
• 911417-25-9 tert-butyl 5-(2-(3-acetoxyphenyl)quinazolin-4-ylamino)-1H-indazole-1-carboxylate 

Relevant articles and documents

RHO KINASE INHIBITORS

The present invention relates to inhibitors of ROCK1 and ROCK2, which may be selective for ROCK2, and methods of modulating the pharmacokinetic and/or pharmacodynamic properties of such compounds. Also provided are methods of inhibiting ROCK1 and/or ROCK2. Also provided are treatments combining inhibitors of ROCK1 and/or ROCK2 with statins.

RHO KINASE INHIBITORS

The present invention relates to inhibitors of ROCKl and R0CK2, which may be selective for R0CK2, and methods of modulating the pharmacokinetic and/or pharmacodynamic properties of such compounds. Also provided are methods of inhibiting ROCKl and/or R0CK2. Also provided are treatments combining inhibitors of ROCKl and/or R0CK2 with statins.

PHARMACOKINETICALLY IMPROVED COMPOUNDS

The present invention relates to inhibitors of ROCKl and R0CK2 and methods of modulating the pharmacokinetic and/or pharmacodynamic properties of such compounds. Also provided are methods of inhibiting ROCKl and or R0CK2 that are useful for the treatment of disease.