911417-62-4

Basic information

• Product Name: Acetic acid, 2-[3-[4-(1H-indazol-5-ylaMino)-2-quinazolinyl]phenoxy]-
• Synonyms: Acetic acid, 2-[3-[4-(1H-indazol-5-ylaMino)-2-quinazolinyl]phenoxy]-;2-(3-(4-((1H-indazol-5-yl)amino)quinazolin-2-yl)phenoxy)acetic acid
• CAS NO: 911417-62-4
• Molecular Formula: C₂₃H₁₇N₅O₃
• Molecular Weight: 411.41278
• Mol File: 911417-62-4.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Acetic acid, 2-[3-[4-(1H-indazol-5-ylaMino)-2-quinazolinyl]phenoxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: Acetic acid, 2-[3-[4-(1H-indazol-5-ylaMino)-2-quinazolinyl]phenoxy]-(911417-62-4)
• EPA Substance Registry System: Acetic acid, 2-[3-[4-(1H-indazol-5-ylaMino)-2-quinazolinyl]phenoxy]-(911417-62-4)

Safety Data

• Hazardous Substances Data: 911417-62-4(Hazardous Substances Data)

Upstream product

• 56071-04-6 2-(3-methoxyphenyl)quinazolin-4(3H)-one 
• 28144-70-9 anthranilic acid amide 
• 1711-05-3 m-anisoyl chloride 
• 911417-24-8 3-(4-chloroquinazolin-2-yl)phenyl acetate 
• 371947-93-2 3-(4-oxo-3,4-dihydroquinazolin-2-yl)phenyl acetate 
• 911417-23-7 2-(3-hydroxylphenyl)quinazolin-4(3H)-one 
• 911417-25-9 tert-butyl 5-(2-(3-acetoxyphenyl)quinazolin-4-ylamino)-1H-indazole-1-carboxylate 

Downstream Products

• 911417-76-0 2-(3-(4-(1H-indazol-5-ylamino)quinazolin-2-yl)phenoxy)-N-(cyclopropylmethyl)acetamide 
• 1024582-78-2 (3S)-tert-butyl 3-(2-(3-(4-(1H-indazol-5-ylamino)quinazolin-2-yl)phenoxy)acetamido)pyrrolidine-1-carboxylate 
• 911417-87-3 2-[3-[4-(1H-indazol-5-ylamino)quinazolin-2-yl]phenoxy]-N-propan-2-ylacetamide 

Relevant articles and documents

PHARMACOKINETICALLY IMPROVED COMPOUNDS

The present invention relates to inhibitors of ROCKl and R0CK2 and methods of modulating the pharmacokinetic and/or pharmacodynamic properties of such compounds. Also provided are methods of inhibiting ROCKl and or R0CK2 that are useful for the treatment of disease.