cas 911855-78-2, (R)-3-methoxy-2-methylpropan-1-ol | Articles data ｜lookchem

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911855-78-2

Articles about 911855-78-2Total 6 be found

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Brettle,Polgar
p. 664,666
(1959)
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SUBSTITUTED PIPERIDINES AS THERAPEUTIC COMPOUNDS
Described are compounds of the general formula (I), and pharmaceutically acceptable salt thereof, in which R1 has the definitions illustrated in detail in the description, as beta-secretase, cathepsin D, plasmepsin II and/or HIV protease inhibi
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Page/Page column 19; 23

(2009/10/30)

Organic compounds
The present invention relates to substituted piperidines of the general formula (I), where R1, R2, R3, R4, R5, Q and X have the definitions elucidated in more detail in the description, to a process for their preparation and to the use of these compounds as medicines, in particular as renin inhibitors. Moreover, the enzymatic substrate portion of the compound is simultaneously a substrate for a membrane transporter.
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Page/Page column 32

(2010/11/30)

Phenyl piperidine derivatives for use as renin inhibitors
Compounds of the general formula and the salts thereof, preferably the pharmaceutically acceptable salts thereof; in which R1 is straight-chain C1-8-alkanoyloxy, straight-chain C1-8-alkoxy, straight-chain C1-8-a
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Page/Page column 8; 10

(2008/06/13)

Bicyclic compounds
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Page/Page column 11; 13

(2010/11/30)

3,4,5-Substituted piperidines as therapeutic compounds
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Page/Page column 77

(2010/11/27)

3,4,5-SUBSTITUTED PIPERIDINES AS RENIN INHIBITORS
The application relates to novel substituted piperidines of the general formula (II) in which R1, R2', R2'', R4', X, Z, m and n have the meanings defined in the description, to a process for the preparation thereof and to the use of these compounds as medicines, especially as renin inhibitors.
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Page/Page column 49

(2008/06/13)

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Chemical Properties

Boiling Point: 162oC
Flash Point:51oC
Density: 0.903
Storage Temp.:2-8°C
PKA: 14.81±0.10(Predicted)
PSA: 29.46000
LogP: 0.26120

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