SYNTHESIS OF OPTICALLY ACTIVE 3-MERCAPTOPYRROLIDINE DERIVATIVES. SYNTHETIC INTERMEDIATES OF CARBAPENEM RS-533 AND ITS ISOMER
The optically active 3-mercaptopyrrolidine derivatives(3a, 3b, 4a and 4b), which are synthetic intermediates of the carbapenem RS-533 (2a) and its isomer (2b), were synthesized by convenient and practical methods.
Shibata, Tomoyuki,Iino, Kimio,Sugimura, Yukio
p. 1331 - 1346
(2007/10/02)
Carbapenem compounds, and compositions containing them
Compounds of formula (I): STR1 [wherein: R1 represents a hydrogen atom, an alkyl group, an alkoxy group or various substituted alkyl groups; R2 represents a group of formula STR2 in which STR3 represents an alicyclic amine group havi
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(2008/06/13)
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