916347-42-7Relevant academic research and scientific papers
Efficient and practical asymmetric synthesis of 1-tert-butyl 3-methyl (3R,4R)-4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1,3-dicarboxylate, a useful intermediate for the synthesis of nociceptin antagonists
Jona, Hideki,Shibata, Jun,Asai, Masanori,Goto, Yasuhiro,Arai, Sachie,Nakajima, Shigeru,Okamoto, Osamu,Kawamoto, Hiroshi,Iwasawa, Yoshikazu
, p. 2439 - 2446 (2009)
An efficient and practical asymmetric synthesis of 1-tert-butyl 3-methyl (3R,4R)-4-(2-oxo-2,3-dihydro-1H-benzimidazol-1-yl)piperidine-1,3-dicarboxylate 1, a useful intermediate for the synthesis of nociceptin antagonists, has been developed. This method i
